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Altered Tau Isoform Ratio Caused by Loss of FUS and SFPQ Function Leads to FTLD-like Phenotypes.
Ishigaki S, Fujioka Y, Okada Y, Riku Y, Udagawa T, Honda D, Yokoi S, Endo K, Ikenaka K, Takagi S, Iguchi Y, Sahara N, Takashima A, Okano H, Yoshida M, Warita H, Aoki M, Watanabe H, Okado H, Katsuno M, Sobue G. Ishigaki S, et al. Among authors: okada y. Cell Rep. 2017 Jan 31;18(5):1118-1131. doi: 10.1016/j.celrep.2017.01.013. Cell Rep. 2017. PMID: 28147269 Free article.
Correlation of insulin resistance and motor function in spinal and bulbar muscular atrophy.
Nakatsuji H, Araki A, Hashizume A, Hijikata Y, Yamada S, Inagaki T, Suzuki K, Banno H, Suga N, Okada Y, Ohyama M, Nakagawa T, Kishida K, Funahashi T, Shimomura I, Okano H, Katsuno M, Sobue G. Nakatsuji H, et al. Among authors: okada y. J Neurol. 2017 May;264(5):839-847. doi: 10.1007/s00415-017-8405-3. Epub 2017 Feb 22. J Neurol. 2017. PMID: 28229243
Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy.
Iida M, Sahashi K, Kondo N, Nakatsuji H, Tohnai G, Tsutsumi Y, Noda S, Murakami A, Onodera K, Okada Y, Nakatochi M, Tsukagoshi Okabe Y, Shimizu S, Mizuno M, Adachi H, Okano H, Sobue G, Katsuno M. Iida M, et al. Among authors: okada y. Nat Commun. 2019 Sep 19;10(1):4262. doi: 10.1038/s41467-019-12282-7. Nat Commun. 2019. PMID: 31537808 Free PMC article.
Unveiling synapse pathology in spinal bulbar muscular atrophy by genome-wide transcriptome analysis of purified motor neurons derived from disease specific iPSCs.
Onodera K, Shimojo D, Ishihara Y, Yano M, Miya F, Banno H, Kuzumaki N, Ito T, Okada R, de Araújo Herculano B, Ohyama M, Yoshida M, Tsunoda T, Katsuno M, Doyu M, Sobue G, Okano H, Okada Y. Onodera K, et al. Among authors: okada r, okada y. Mol Brain. 2020 Feb 19;13(1):18. doi: 10.1186/s13041-020-0561-1. Mol Brain. 2020. PMID: 32070397 Free PMC article.
A multi-ethnic meta-analysis identifies novel genes, including ACSL5, associated with amyotrophic lateral sclerosis.
Nakamura R, Misawa K, Tohnai G, Nakatochi M, Furuhashi S, Atsuta N, Hayashi N, Yokoi D, Watanabe H, Watanabe H, Katsuno M, Izumi Y, Kanai K, Hattori N, Morita M, Taniguchi A, Kano O, Oda M, Shibuya K, Kuwabara S, Suzuki N, Aoki M, Ohta Y, Yamashita T, Abe K, Hashimoto R, Aiba I, Okamoto K, Mizoguchi K, Hasegawa K, Okada Y, Ishihara T, Onodera O, Nakashima K, Kaji R, Kamatani Y, Ikegawa S, Momozawa Y, Kubo M, Ishida N, Minegishi N, Nagasaki M, Sobue G. Nakamura R, et al. Among authors: okada y. Commun Biol. 2020 Sep 23;3(1):526. doi: 10.1038/s42003-020-01251-2. Commun Biol. 2020. PMID: 32968195 Free PMC article.
The SYNGAP1 3'UTR Variant in ALS Patients Causes Aberrant SYNGAP1 Splicing and Dendritic Spine Loss by Recruiting HNRNPK.
Yokoi S, Ito T, Sahashi K, Nakatochi M, Nakamura R, Tohnai G, Fujioka Y, Ishigaki S, Udagawa T, Izumi Y, Morita M, Kano O, Oda M, Sone T, Okano H, Atsuta N, Katsuno M, Okada Y, Sobue G. Yokoi S, et al. Among authors: okada y. J Neurosci. 2022 Nov 23;42(47):8881-8896. doi: 10.1523/JNEUROSCI.0455-22.2022. Epub 2022 Oct 19. J Neurosci. 2022. PMID: 36261283 Free PMC article.
Simple and efficient differentiation of human iPSCs into contractible skeletal muscles for muscular disease modeling.
Rashid MI, Ito T, Miya F, Shimojo D, Arimoto K, Onodera K, Okada R, Nagashima T, Yamamoto K, Khatun Z, Shimul RI, Niwa JI, Katsuno M, Sobue G, Okano H, Sakurai H, Shimizu K, Doyu M, Okada Y. Rashid MI, et al. Among authors: okada r, okada y. Sci Rep. 2023 May 25;13(1):8146. doi: 10.1038/s41598-023-34445-9. Sci Rep. 2023. PMID: 37231024 Free PMC article.
7,093 results