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His452Tyr polymorphism in the human 5-HT2A receptor affects clozapine-induced signaling networks revealed by quantitative phosphoproteomics.
Martín-Guerrero SM, Alonso P, Iglesias A, Cimadevila M, Brea J, Loza MI, Casado P, Martín-Oliva D, Cutillas PR, González-Maeso J, López-Giménez JF. Martín-Guerrero SM, et al. Among authors: lopez gimenez jf. Biochem Pharmacol. 2021 Mar;185:114440. doi: 10.1016/j.bcp.2021.114440. Epub 2021 Feb 1. Biochem Pharmacol. 2021. PMID: 33539816
Interclass GPCR heteromerization affects localization and trafficking.
Toneatti R, Shin JM, Shah UH, Mayer CR, Saunders JM, Fribourg M, Arsenovic PT, Janssen WG, Sealfon SC, López-Giménez JF, Benson DL, Conway DE, González-Maeso J. Toneatti R, et al. Among authors: lopez gimenez jf. Sci Signal. 2020 Oct 20;13(654):eaaw3122. doi: 10.1126/scisignal.aaw3122. Sci Signal. 2020. PMID: 33082287 Free PMC article.
Poly(ADP-Ribose) Polymerase-1 inhibition potentiates cell death and phosphorylation of DNA damage response proteins in oxidative stressed retinal cells.
Martín-Guerrero SM, Casado P, Muñoz-Gámez JA, Carrasco MC, Navascués J, Cuadros MA, López-Giménez JF, Cutillas PR, Martín-Oliva D. Martín-Guerrero SM, et al. Among authors: lopez gimenez jf. Exp Eye Res. 2019 Nov;188:107790. doi: 10.1016/j.exer.2019.107790. Epub 2019 Sep 5. Exp Eye Res. 2019. PMID: 31494107
Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia.
Moreno JL, Miranda-Azpiazu P, García-Bea A, Younkin J, Cui M, Kozlenkov A, Ben-Ezra A, Voloudakis G, Fakira AK, Baki L, Ge Y, Georgakopoulos A, Morón JA, Milligan G, López-Giménez JF, Robakis NK, Logothetis DE, Meana JJ, González-Maeso J. Moreno JL, et al. Among authors: lopez gimenez jf. Sci Signal. 2016 Jan 12;9(410):ra5. doi: 10.1126/scisignal.aab0467. Sci Signal. 2016. PMID: 26758213 Free PMC article.
Identification of a serotonin/glutamate receptor complex implicated in psychosis.
González-Maeso J, Ang RL, Yuen T, Chan P, Weisstaub NV, López-Giménez JF, Zhou M, Okawa Y, Callado LF, Milligan G, Gingrich JA, Filizola M, Meana JJ, Sealfon SC. González-Maeso J, et al. Nature. 2008 Mar 6;452(7183):93-7. doi: 10.1038/nature06612. Epub 2008 Feb 24. Nature. 2008. PMID: 18297054 Free PMC article.
43 results