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Improved prediction of fracture risk leveraging a genome-wide polygenic risk score.
Lu T, Forgetta V, Keller-Baruch J, Nethander M, Bennett D, Forest M, Bhatnagar S, Walters RG, Lin K, Chen Z, Li L, Karlsson M, Mellström D, Orwoll E, McCloskey EV, Kanis JA, Leslie WD, Clarke RJ, Ohlsson C, Greenwood CMT, Richards JB. Lu T, et al. Among authors: leslie wd. Genome Med. 2021 Feb 3;13(1):16. doi: 10.1186/s13073-021-00838-6. Genome Med. 2021. PMID: 33536041 Free PMC article.
Changes to osteoporosis prevalence according to method of risk assessment.
Richards JB, Leslie WD, Joseph L, Siminoski K, Hanley DA, Adachi JD, Brown JP, Morin S, Papaioannou A, Josse RG, Prior JC, Davison KS, Tenenhouse A, Goltzman D; CaMos Study Group. Richards JB, et al. Among authors: leslie wd. J Bone Miner Res. 2007 Feb;22(2):228-34. doi: 10.1359/jbmr.061109. J Bone Miner Res. 2007. PMID: 17129177 Free article.
Using the same bone density reference database for men and women provides a simpler estimation of fracture risk.
Langsetmo L, Leslie WD, Zhou W, Goltzman D, Kovacs CS, Prior J, Josse R, Olszynski WP, Davison KS, Anastassiades T, Towheed T, Hanley DA, Kaiser S, Kreiger N; CaMOS Research Group. Langsetmo L, et al. Among authors: leslie wd. J Bone Miner Res. 2010 Oct;25(10):2108-14. doi: 10.1002/jbmr.112. J Bone Miner Res. 2010. PMID: 20499356 Free PMC article.
An efficient paradigm for genetic epidemiology cohort creation.
Ladouceur M, Leslie WD, Dastani Z, Goltzman D, Richards JB. Ladouceur M, et al. Among authors: leslie wd. PLoS One. 2010 Nov 18;5(11):e14045. doi: 10.1371/journal.pone.0014045. PLoS One. 2010. PMID: 21124974 Free PMC article.
Fracture prediction and calibration of a Canadian FRAX® tool: a population-based report from CaMos.
Fraser LA, Langsetmo L, Berger C, Ioannidis G, Goltzman D, Adachi JD, Papaioannou A, Josse R, Kovacs CS, Olszynski WP, Towheed T, Hanley DA, Kaiser SM, Prior J, Jamal S, Kreiger N, Brown JP, Johansson H, Oden A, McCloskey E, Kanis JA, Leslie WD; CaMos Research Group. Fraser LA, et al. Among authors: leslie wd. Osteoporos Int. 2011 Mar;22(3):829-37. doi: 10.1007/s00198-010-1465-1. Epub 2010 Dec 16. Osteoporos Int. 2011. PMID: 21161508 Free PMC article.
570 results