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In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene.
Larochelle A, Choi U, Shou Y, Naumann N, Loktionova NA, Clevenger JR, Krouse A, Metzger M, Donahue RE, Kang E, Stewart C, Persons D, Malech HL, Dunbar CE, Sorrentino BP. Larochelle A, et al. J Clin Invest. 2009 Jul;119(7):1952-63. doi: 10.1172/JCI37506. Epub 2009 Jun 8. J Clin Invest. 2009. PMID: 19509470 Free PMC article.
Eltrombopag promotes DNA repair in human hematopoietic stem and progenitor cells.
Guenther KL, Cheruku PS, Cash A, Smith RH, Alvarado LJ, Burkett S, Townsley DM, Winkler T, Larochelle A. Guenther KL, et al. Among authors: larochelle a. Exp Hematol. 2019 May;73:1-6.e6. doi: 10.1016/j.exphem.2019.03.002. Epub 2019 Apr 13. Exp Hematol. 2019. PMID: 30986494 Free PMC article.
Preclinical Evaluation of Foamy Virus Vector-Mediated Gene Addition in Human Hematopoietic Stem/Progenitor Cells for Correction of Leukocyte Adhesion Deficiency Type 1.
Smith RH, Bloomer H, Fink D, Keyvanfar K, Nasimuzzaman M, Sancheznieto F, Dutta R, Guenther Bui K, Alvarado LJ, Bauer TR Jr, Hickstein DD, Russell DW, Malik P, van der Loo JCM, Highfill SL, Kuhns DB, Pirooznia M, Larochelle A. Smith RH, et al. Among authors: larochelle a. Hum Gene Ther. 2022 Dec;33(23-24):1293-1304. doi: 10.1089/hum.2022.065. Epub 2022 Nov 1. Hum Gene Ther. 2022. PMID: 36094106 Free PMC article.
Ex vivo culture resting time impacts transplantation outcomes of genome-edited human hematopoietic stem and progenitor cells in xenograft mouse models.
Demirci S, Khan MBN, Hinojosa G, Le A, Leonard A, Essawi K, Gudmundsdottir B, Liu X, Zeng J, Inam Z, Chu R, Uchida N, Araki D, London E, Butt H, Maitland SA, Bauer DE, Wolfe SA, Larochelle A, Tisdale JF. Demirci S, et al. Among authors: larochelle a. Cytotherapy. 2024 Jun;26(6):641-648. doi: 10.1016/j.jcyt.2024.02.011. Epub 2024 Feb 24. Cytotherapy. 2024. PMID: 38506770
Genetic manipulation of hematopoietic stem cells.
Larochelle A, Dunbar CE. Larochelle A, et al. Semin Hematol. 2004 Oct;41(4):257-71. doi: 10.1053/j.seminhematol.2004.07.002. Semin Hematol. 2004. PMID: 15508111 Review.
Hematopoietic stem cell gene therapy: dead or alive?
Ferguson C, Larochelle A, Dunbar CE. Ferguson C, et al. Among authors: larochelle a. Trends Biotechnol. 2005 Dec;23(12):589-97. doi: 10.1016/j.tibtech.2005.09.005. Epub 2005 Oct 10. Trends Biotechnol. 2005. PMID: 16216357 Review.
98 results