Longo F - Search Results

1

Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity, and memory in mouse models of Alzheimer's disease.

Oliveira MM, Lourenco MV, Longo F, Kasica NP, Yang W, Ureta G, Ferreira DDP, Mendonça PHJ, Bernales S, Ma T, De Felice FG, Klann E, Ferreira ST. Oliveira MM, et al. Among authors: longo f. Sci Signal. 2021 Feb 2;14(668):eabc5429. doi: 10.1126/scisignal.abc5429. Sci Signal. 2021. PMID: 33531382 Free PMC article.

2

Reducing eIF4E-eIF4G interactions restores the balance between protein synthesis and actin dynamics in fragile X syndrome model mice.

Santini E, Huynh TN, Longo F, Koo SY, Mojica E, D'Andrea L, Bagni C, Klann E. Santini E, et al. Among authors: longo f. Sci Signal. 2017 Nov 7;10(504):eaan0665. doi: 10.1126/scisignal.aan0665. Sci Signal. 2017. PMID: 29114037 Free PMC article.

3

Inositol polyphosphate multikinase mediates extinction of fear memory.

Park J, Longo F, Park SJ, Lee S, Bae M, Tyagi R, Han JH, Kim S, Santini E, Klann E, Snyder SH. Park J, et al. Among authors: longo f. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2707-2712. doi: 10.1073/pnas.1812771116. Epub 2019 Jan 28. Proc Natl Acad Sci U S A. 2019. PMID: 30692248 Free PMC article.

4

UPF2 leads to degradation of dendritically targeted mRNAs to regulate synaptic plasticity and cognitive function.

Notaras M, Allen M, Longo F, Volk N, Toth M, Li Jeon N, Klann E, Colak D. Notaras M, et al. Among authors: longo f. Mol Psychiatry. 2020 Dec;25(12):3360-3379. doi: 10.1038/s41380-019-0547-5. Epub 2019 Oct 21. Mol Psychiatry. 2020. PMID: 31636381 Free PMC article.

5

Cell-type-specific drug-inducible protein synthesis inhibition demonstrates that memory consolidation requires rapid neuronal translation.

Shrestha P, Ayata P, Herrero-Vidal P, Longo F, Gastone A, LeDoux JE, Heintz N, Klann E. Shrestha P, et al. Among authors: longo f. Nat Neurosci. 2020 Feb;23(2):281-292. doi: 10.1038/s41593-019-0568-z. Epub 2020 Jan 20. Nat Neurosci. 2020. PMID: 31959934 Free PMC article.

6

Cell-type-specific disruption of PERK-eIF2α signaling in dopaminergic neurons alters motor and cognitive function.

Longo F, Mancini M, Ibraheem PL, Aryal S, Mesini C, Patel JC, Penhos E, Rahman N, Mamcarz M, Santini E, Rice ME, Klann E. Longo F, et al. Mol Psychiatry. 2021 Nov;26(11):6427-6450. doi: 10.1038/s41380-021-01099-w. Epub 2021 Apr 20. Mol Psychiatry. 2021. PMID: 33879865 Free PMC article.

7

Genetic removal of p70 S6K1 corrects coding sequence length-dependent alterations in mRNA translation in fragile X syndrome mice.

Aryal S, Longo F, Klann E. Aryal S, et al. Among authors: longo f. Proc Natl Acad Sci U S A. 2021 May 4;118(18):e2001681118. doi: 10.1073/pnas.2001681118. Proc Natl Acad Sci U S A. 2021. PMID: 33906942 Free PMC article.

8

Reciprocal control of translation and transcription in autism spectrum disorder.

Longo F, Klann E. Longo F, et al. EMBO Rep. 2021 Jun 4;22(6):e52110. doi: 10.15252/embr.202052110. Epub 2021 May 11. EMBO Rep. 2021. PMID: 33977633 Free PMC article. Review.

9

Astrocytes derived from ASD individuals alter behavior and destabilize neuronal activity through aberrant Ca²⁺ signaling.

Allen M, Huang BS, Notaras MJ, Lodhi A, Barrio-Alonso E, Lituma PJ, Wolujewicz P, Witztum J, Longo F, Chen M, Greening DW, Klann E, Ross ME, Liston C, Colak D. Allen M, et al. Among authors: longo f. Mol Psychiatry. 2022 May;27(5):2470-2484. doi: 10.1038/s41380-022-01486-x. Epub 2022 Apr 1. Mol Psychiatry. 2022. PMID: 35365802 Free PMC article.

10

Deletion of Fmr1 in parvalbumin-expressing neurons results in dysregulated translation and selective behavioral deficits associated with fragile X syndrome.

Kalinowska M, van der Lei MB, Kitiashvili M, Mamcarz M, Oliveira MM, Longo F, Klann E. Kalinowska M, et al. Among authors: longo f. Mol Autism. 2022 Jun 29;13(1):29. doi: 10.1186/s13229-022-00509-2. Mol Autism. 2022. PMID: 35768828 Free PMC article.

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