Bignon J - Search Results

1

Facile Synthesis of Amphiphilic Fluorescent Phosphorus Dendron-Based Micelles as Antiproliferative Agents: First Investigations.

Qiu J, Chen L, Zhan M, Laurent R, Bignon J, Mignani S, Shi X, Caminade AM, Majoral JP. Qiu J, et al. Among authors: bignon j. Bioconjug Chem. 2021 Feb 17;32(2):339-349. doi: 10.1021/acs.bioconjchem.0c00716. Epub 2021 Jan 31. Bioconjug Chem. 2021. PMID: 33522223

2

New C5-alkylated indolobenzazepinones acting as inhibitors of tubulin polymerization: cytotoxic and antitumor activities.

Keller L, Beaumont S, Liu JM, Thoret S, Bignon JS, Wdzieczak-Bakala J, Dauban P, Dodd RH. Keller L, et al. Among authors: bignon js. J Med Chem. 2008 Jun 26;51(12):3414-21. doi: 10.1021/jm701466p. Epub 2008 May 27. J Med Chem. 2008. PMID: 18503262

3

Synthesis and biological evaluation of a new series of highly functionalized 7'-homo-anhydrovinblastine derivatives.

Gherbovet O, Coderch C, García Alvarez MC, Bignon J, Thoret S, Martin MT, Guéritte F, Gago F, Roussi F. Gherbovet O, et al. Among authors: bignon j. J Med Chem. 2013 Aug 8;56(15):6088-100. doi: 10.1021/jm4004347. Epub 2013 Jul 18. J Med Chem. 2013. PMID: 23822556

4

One-pot synthesis of vinca alkaloids-phomopsin hybrids.

Gherbovet O, Coderch C, García Alvarez MC, Bignon J, Thoret S, Guéritte F, Gago F, Roussi F. Gherbovet O, et al. Among authors: bignon j. J Med Chem. 2014 Jun 26;57(12):5470-6. doi: 10.1021/jm500530v. Epub 2014 Jun 10. J Med Chem. 2014. PMID: 24871162

5

A New Series of Succinimido-ferrociphenols and Related Heterocyclic Species Induce Strong Antiproliferative Effects, Especially against Ovarian Cancer Cells Resistant to Cisplatin.

Pigeon P, Wang Y, Top S, Najlaoui F, Garcia Alvarez MC, Bignon J, McGlinchey MJ, Jaouen G. Pigeon P, et al. Among authors: bignon j. J Med Chem. 2017 Oct 26;60(20):8358-8368. doi: 10.1021/acs.jmedchem.7b00743. Epub 2017 Sep 22. J Med Chem. 2017. PMID: 28895732

6

Inhibition of p53-Murine Double Minute 2 (MDM2) Interactions with 3,3'-Spirocyclopentene Oxindole Derivatives.

Gicquel M, Gomez C, Garcia Alvarez MC, Pamlard O, Guérineau V, Jacquet E, Bignon J, Voituriez A, Marinetti A. Gicquel M, et al. Among authors: bignon j. J Med Chem. 2018 Oct 25;61(20):9386-9392. doi: 10.1021/acs.jmedchem.8b01137. Epub 2018 Oct 8. J Med Chem. 2018. PMID: 30221935

7

Potent Anticancer Efficacy of First-In-Class Cu^II and Au^III Metaled Phosphorus Dendrons with Distinct Cell Death Pathways.

Chen L, Fan Y, Qiu J, Laurent R, Li J, Bignon J, Mignani S, Caminade AM, Shi X, Majoral JP. Chen L, et al. Among authors: bignon j. Chemistry. 2020 May 7;26(26):5903-5910. doi: 10.1002/chem.202001014. Epub 2020 Apr 21. Chemistry. 2020. PMID: 32142179

8

Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation.

Pecnard S, Provot O, Levaique H, Bignon J, Askenatzis L, Saller F, Borgel D, Michallet S, Laisne MC, Lafanechère L, Alami M, Hamze A. Pecnard S, et al. Among authors: bignon j. Eur J Med Chem. 2021 Jan 1;209:112873. doi: 10.1016/j.ejmech.2020.112873. Epub 2020 Oct 4. Eur J Med Chem. 2021. PMID: 33038796

9

First-in-Class Phosphorus Dendritic Framework, a Wide Surface Functional Group Palette Bringing Noteworthy Anti-Cancer and Anti-Tuberculosis Activities: What Lessons to Learn?

Mignani S, Bignon J, Shi X, Majoral JP. Mignani S, et al. Among authors: bignon j. Molecules. 2021 Jun 17;26(12):3708. doi: 10.3390/molecules26123708. Molecules. 2021. PMID: 34204564 Free PMC article. Review.

10

Synthesis and evaluation of a novel class of ethacrynic acid derivatives containing triazoles as potent anticancer agents.

El Abbouchi A, El Brahmi N, Hiebel MA, Bignon J, Guillaumet G, Suzenet F, El Kazzouli S. El Abbouchi A, et al. Among authors: bignon j. Bioorg Chem. 2021 Oct;115:105293. doi: 10.1016/j.bioorg.2021.105293. Epub 2021 Aug 20. Bioorg Chem. 2021. PMID: 34426162

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