Leitges M - Search Results

1

Dysfunctional EGFR and oxidative stress-induced PKD1 signaling drive formation of DCLK1+ pancreatic stem cells.

Fleming Martinez AK, Döppler HR, Bastea LI, Edenfield B, Patel T, Leitges M, Liou GY, Storz P. Fleming Martinez AK, et al. Among authors: leitges m. iScience. 2021 Jan 5;24(1):102019. doi: 10.1016/j.isci.2020.102019. eCollection 2021 Jan 22. iScience. 2021. PMID: 33521594 Free PMC article.

2

Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia.

Liou GY, Döppler H, Braun UB, Panayiotou R, Scotti Buzhardt M, Radisky DC, Crawford HC, Fields AP, Murray NR, Wang QJ, Leitges M, Storz P. Liou GY, et al. Among authors: leitges m. Nat Commun. 2015 Feb 20;6:6200. doi: 10.1038/ncomms7200. Nat Commun. 2015. PMID: 25698580 Free PMC article.

3

Pancreatic oncogenic signaling cascades converge at Protein Kinase D1.

Liou GY, Leitges M, Storz P. Liou GY, et al. Among authors: leitges m. Cell Cycle. 2015;14(10):1489-90. doi: 10.1080/15384101.2015.1032646. Cell Cycle. 2015. PMID: 25928263 Free PMC article. No abstract available.

4

Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions.

Liou GY, Döppler H, DelGiorno KE, Zhang L, Leitges M, Crawford HC, Murphy MP, Storz P. Liou GY, et al. Among authors: leitges m. Cell Rep. 2016 Mar 15;14(10):2325-36. doi: 10.1016/j.celrep.2016.02.029. Epub 2016 Mar 3. Cell Rep. 2016. PMID: 26947075 Free PMC article.

5

A bright future for protein kinase D1 as a drug target to prevent or treat pancreatic cancer.

Liou GY, Storz P, Leitges M. Liou GY, et al. Among authors: leitges m. Mol Cell Oncol. 2015 Dec 10;3(1):e1035477. doi: 10.1080/23723556.2015.1035477. eCollection 2016 Jan. Mol Cell Oncol. 2015. PMID: 27308552 Free PMC article.

6

Protein kinase Cα suppresses Kras-mediated lung tumor formation through activation of a p38 MAPK-TGFβ signaling axis.

Hill KS, Erdogan E, Khoor A, Walsh MP, Leitges M, Murray NR, Fields AP. Hill KS, et al. Among authors: leitges m. Oncogene. 2014 Apr 17;33(16):2134-44. doi: 10.1038/onc.2013.147. Epub 2013 Apr 22. Oncogene. 2014. PMID: 23604119 Free PMC article.

7

Prkci Regulates Autophagy and Pancreatic Tumorigenesis in Mice.

Inman KS, Liu Y, Scotti Buzhardt ML, Leitges M, Krishna M, Crawford HC, Fields AP, Murray NR. Inman KS, et al. Among authors: leitges m. Cancers (Basel). 2022 Feb 4;14(3):796. doi: 10.3390/cancers14030796. Cancers (Basel). 2022. PMID: 35159064 Free PMC article.

8

Protein kinase C-β-dependent changes in the glucose metabolism of bone marrow stromal cells of chronic lymphocytic leukemia.

von Heydebrand F, Fuchs M, Kunz M, Voelkl S, Kremer AN, Oostendorp RAJ, Wilke J, Leitges M, Egle A, Mackensen A, Lutzny-Geier G. von Heydebrand F, et al. Among authors: leitges m. Stem Cells. 2021 Jun;39(6):819-830. doi: 10.1002/stem.3352. Epub 2021 Feb 17. Stem Cells. 2021. PMID: 33539629

9

Protein kinase C_ι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities.

Kenchappa RS, Liu Y, Argenziano MG, Banu MA, Mladek AC, West R, Luu A, Quiñones-Hinojosa A, Hambardzumyan D, Justilien V, Leitges M, Sarkaria JN, Sims PA, Canoll P, Murray NR, Fields AP, Rosenfeld SS. Kenchappa RS, et al. Among authors: leitges m. Cell Rep. 2021 Nov 23;37(8):110054. doi: 10.1016/j.celrep.2021.110054. Cell Rep. 2021. PMID: 34818553 Free PMC article.

10

Protein Kinase Cι and Wnt/β-Catenin Signaling: Alternative Pathways to Kras/Trp53-Driven Lung Adenocarcinoma.

Yin N, Liu Y, Khoor A, Wang X, Thompson EA, Leitges M, Justilien V, Weems C, Murray NR, Fields AP. Yin N, et al. Among authors: leitges m. Cancer Cell. 2019 Aug 12;36(2):156-167.e7. doi: 10.1016/j.ccell.2019.07.002. Epub 2019 Aug 1. Cancer Cell. 2019. PMID: 31378680 Free PMC article.

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