Chen CT - Search Results

1

Inhibition of SARS-CoV-2 by Highly Potent Broad-Spectrum Anti-Coronaviral Tylophorine-Based Derivatives.

Yang CW, Lee YZ, Hsu HY, Jan JT, Lin YL, Chang SY, Peng TT, Yang RB, Liang JJ, Liao CC, Chao TL, Pang YH, Kao HC, Huang WZ, Lin JH, Chang CP, Niu GH, Wu SH, Sytwu HK, Chen CT, Lee SJ. Yang CW, et al. Among authors: chen ct. Front Pharmacol. 2020 Dec 14;11:606097. doi: 10.3389/fphar.2020.606097. eCollection 2020. Front Pharmacol. 2020. PMID: 33519469 Free PMC article.

2

BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.

Kuo CC, Hsieh HP, Pan WY, Chen CP, Liou JP, Lee SJ, Chang YL, Chen LT, Chen CT, Chang JY. Kuo CC, et al. Among authors: chen ct, chen lt, chen cp. Cancer Res. 2004 Jul 1;64(13):4621-8. doi: 10.1158/0008-5472.CAN-03-3474. Cancer Res. 2004. PMID: 15231674

3

Discovery of non-glycoside sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors by ligand-based virtual screening.

Wu JS, Peng YH, Wu JM, Hsieh CJ, Wu SH, Coumar MS, Song JS, Lee JC, Tsai CH, Chen CT, Liu YW, Chao YS, Wu SY. Wu JS, et al. Among authors: chen ct. J Med Chem. 2010 Dec 23;53(24):8770-4. doi: 10.1021/jm101080v. Epub 2010 Nov 19. J Med Chem. 2010. PMID: 21090651

4

Discovery of novel N-β-D-xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes.

Yao CH, Song JS, Chen CT, Yeh TK, Hung MS, Chang CC, Liu YW, Yuan MC, Hsieh CJ, Huang CY, Wang MH, Chiu CH, Hsieh TC, Wu SH, Hsiao WC, Chu KF, Tsai CH, Chao YS, Lee JC. Yao CH, et al. Among authors: chen ct. J Med Chem. 2011 Jan 13;54(1):166-78. doi: 10.1021/jm101072y. Epub 2010 Dec 3. J Med Chem. 2011. PMID: 21128592

5

Discovery of novel stem cell mobilizers that target the CXCR4 receptor.

Wu CH, Chang CP, Song JS, Jan JJ, Chou MC, Wu SH, Yeh KC, Wong YC, Hsieh CJ, Chen CT, Kao TT, Wu SY, Yeh CF, Tseng CT, Chao YS, Shia KS. Wu CH, et al. Among authors: chen ct. ChemMedChem. 2012 Feb 6;7(2):209-12. doi: 10.1002/cmdc.201100525. Epub 2011 Dec 20. ChemMedChem. 2012. PMID: 22190478 No abstract available.

6

Synthesis and biological evaluation of novel C-indolylxylosides as sodium-dependent glucose co-transporter 2 inhibitors.

Yao CH, Song JS, Chen CT, Yeh TK, Hsieh TC, Wu SH, Huang CY, Huang YL, Wang MH, Liu YW, Tsai CH, Kumar CR, Lee JC. Yao CH, et al. Among authors: chen ct. Eur J Med Chem. 2012 Sep;55:32-8. doi: 10.1016/j.ejmech.2012.06.053. Epub 2012 Jul 4. Eur J Med Chem. 2012. PMID: 22818040

7

Stem cell mobilizers targeting chemokine receptor CXCR4: renoprotective application in acute kidney injury.

Wu CH, Song JS, Chang KH, Jan JJ, Chen CT, Chou MC, Yeh KC, Wong YC, Tseng CT, Wu SH, Yeh CF, Huang CY, Wang MH, Sadani AA, Chang CP, Cheng CY, Tsou LK, Shia KS. Wu CH, et al. Among authors: chen ct. J Med Chem. 2015 Mar 12;58(5):2315-25. doi: 10.1021/jm501769r. Epub 2015 Mar 2. J Med Chem. 2015. PMID: 25686267

8

N-Indolylglycosides bearing modifications at the glucose C6-position as sodium-dependent glucose co-transporter 2 inhibitors.

Chu KF, Yao CH, Song JS, Chen CT, Yeh TK, Hsieh TC, Huang CY, Wang MH, Wu SH, Chang WE, Chao YS, Lee JC. Chu KF, et al. Among authors: chen ct. Bioorg Med Chem. 2016 May 15;24(10):2242-50. doi: 10.1016/j.bmc.2016.03.058. Epub 2016 Mar 30. Bioorg Med Chem. 2016. PMID: 27075813

9

Design, Synthesis, and Evaluation of Thiazolidine-2,4-dione Derivatives as a Novel Class of Glutaminase Inhibitors.

Yeh TK, Kuo CC, Lee YZ, Ke YY, Chu KF, Hsu HY, Chang HY, Liu YW, Song JS, Yang CW, Lin LM, Sun M, Wu SH, Kuo PC, Shih C, Chen CT, Tsou LK, Lee SJ. Yeh TK, et al. Among authors: chen ct. J Med Chem. 2017 Jul 13;60(13):5599-5612. doi: 10.1021/acs.jmedchem.7b00282. Epub 2017 Jun 29. J Med Chem. 2017. PMID: 28609101

10

Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2.

Yuan MC, Yeh TK, Chen CT, Song JS, Huang YC, Hsieh TC, Huang CY, Huang YL, Wang MH, Wu SH, Yao CH, Chao YS, Lee JC. Yuan MC, et al. Among authors: chen ct. Eur J Med Chem. 2018 Jan 1;143:611-620. doi: 10.1016/j.ejmech.2017.11.019. Epub 2017 Nov 10. Eur J Med Chem. 2018. PMID: 29216560

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