Mole DR - Search Results

1

Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter.

Wing PAC, Liu PJ, Harris JM, Magri A, Michler T, Zhuang X, Borrmann H, Minisini R, Frampton NR, Wettengel JM, Mailly L, D'Arienzo V, Riedl T, Nobre L, Weekes MP, Pirisi M, Heikenwalder M, Baumert TF, Hammond EM, Mole DR, Protzer U, Balfe P, McKeating JA. Wing PAC, et al. Among authors: mole dr. J Hepatol. 2021 Jul;75(1):64-73. doi: 10.1016/j.jhep.2020.12.034. Epub 2021 Jan 29. J Hepatol. 2021. PMID: 33516779 Free PMC article.

2

Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α).

Thalhammer A, Bencokova Z, Poole R, Loenarz C, Adam J, O'Flaherty L, Schödel J, Mole D, Giaslakiotis K, Schofield CJ, Hammond EM, Ratcliffe PJ, Pollard PJ. Thalhammer A, et al. PLoS One. 2011 Jan 14;6(1):e16210. doi: 10.1371/journal.pone.0016210. PLoS One. 2011. PMID: 21264265 Free PMC article.

3

Hypoxic microenvironment shapes HIV-1 replication and latency.

Zhuang X, Pedroza-Pacheco I, Nawroth I, Kliszczak AE, Magri A, Paes W, Rubio CO, Yang H, Ashcroft M, Mole D, Balfe P, Borrow P, McKeating JA. Zhuang X, et al. Commun Biol. 2020 Jul 14;3(1):376. doi: 10.1038/s42003-020-1103-1. Commun Biol. 2020. PMID: 32665623 Free PMC article.

4

Novel mechanism of action for hydralazine: induction of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases.

Knowles HJ, Tian YM, Mole DR, Harris AL. Knowles HJ, et al. Among authors: mole dr. Circ Res. 2004 Jul 23;95(2):162-9. doi: 10.1161/01.RES.0000134924.89412.70. Epub 2004 Jun 10. Circ Res. 2004. PMID: 15192023

5

Hypoxia-inducible factors: where, when and why?

Gleadle JM, Mole DR, Pugh CW. Gleadle JM, et al. Among authors: mole dr. Kidney Int. 2006 Jan;69(1):15-7. doi: 10.1038/sj.ki.5000072. Kidney Int. 2006. PMID: 16374417 Free article.

6

Normoxic stabilization of hypoxia-inducible factor-1alpha by modulation of the labile iron pool in differentiating U937 macrophages: effect of natural resistance-associated macrophage protein 1.

Knowles HJ, Mole DR, Ratcliffe PJ, Harris AL. Knowles HJ, et al. Among authors: mole dr. Cancer Res. 2006 Mar 1;66(5):2600-7. doi: 10.1158/0008-5472.CAN-05-2351. Cancer Res. 2006. PMID: 16510578

7

Cellular oxygen sensing in health and disease.

Mole DR, Ratcliffe PJ. Mole DR, et al. Pediatr Nephrol. 2008 May;23(5):681-94. doi: 10.1007/s00467-007-0632-x. Epub 2007 Oct 23. Pediatr Nephrol. 2008. PMID: 17955264 Review.

8

Regulation of type II transmembrane serine proteinase TMPRSS6 by hypoxia-inducible factors: new link between hypoxia signaling and iron homeostasis.

Lakhal S, Schödel J, Townsend AR, Pugh CW, Ratcliffe PJ, Mole DR. Lakhal S, et al. Among authors: mole dr. J Biol Chem. 2011 Feb 11;286(6):4090-7. doi: 10.1074/jbc.M110.173096. Epub 2010 Oct 21. J Biol Chem. 2011. PMID: 20966077 Free PMC article.

9

Pan-genomic binding of hypoxia-inducible transcription factors.

Schödel J, Mole DR, Ratcliffe PJ. Schödel J, et al. Among authors: mole dr. Biol Chem. 2013 Apr;394(4):507-17. doi: 10.1515/hsz-2012-0351. Biol Chem. 2013. PMID: 23324384 Review.

10

Heterogeneous Effects of Direct Hypoxia Pathway Activation in Kidney Cancer.

Salama R, Masson N, Simpson P, Sciesielski LK, Sun M, Tian YM, Ratcliffe PJ, Mole DR. Salama R, et al. Among authors: mole dr. PLoS One. 2015 Aug 11;10(8):e0134645. doi: 10.1371/journal.pone.0134645. eCollection 2015. PLoS One. 2015. PMID: 26262842 Free PMC article.

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