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Lentiviral vector ALS20 yields high hemoglobin levels with low genomic integrations for treatment of beta-globinopathies.
Breda L, Ghiaccio V, Tanaka N, Jarocha D, Ikawa Y, Abdulmalik O, Dong A, Casu C, Raabe TD, Shan X, Danet-Desnoyers GA, Doto AM, Everett J, Bushman FD, Radaelli E, Assenmacher CA, Tarrant JC, Hoepp N, Kurita R, Nakamura Y, Guzikowski V, Smith-Whitley K, Kwiatkowski JL, Rivella S. Breda L, et al. Among authors: tarrant jc. Mol Ther. 2021 Apr 7;29(4):1625-1638. doi: 10.1016/j.ymthe.2020.12.036. Epub 2021 Jan 29. Mol Ther. 2021. PMID: 33515514 Free PMC article.
Spontaneous Incidental Brain Lesions in C57BL/6J Mice.
Tarrant JC, Savickas P, Omodho L, Spinazzi M, Radaelli E. Tarrant JC, et al. Vet Pathol. 2020 Jan;57(1):172-182. doi: 10.1177/0300985819859878. Epub 2019 Jul 4. Vet Pathol. 2020. PMID: 31272300
Pathology of macrophage activation syndrome in humanized NSGS mice.
Tarrant JC, Binder ZA, Bugatti M, Vermi W, van den Oord J, Ranieri B, Assenmacher CA, Hoepp N, O'Rourke DM, Shan X, Danet-Desnoyers G, Radaelli E. Tarrant JC, et al. Res Vet Sci. 2021 Jan;134:137-146. doi: 10.1016/j.rvsc.2020.12.003. Epub 2020 Dec 16. Res Vet Sci. 2021. PMID: 33383491
Mechanisms of Regulated Cell Death: Current Perspectives.
Santagostino SF, Assenmacher CA, Tarrant JC, Adedeji AO, Radaelli E. Santagostino SF, et al. Among authors: tarrant jc. Vet Pathol. 2021 Jul;58(4):596-623. doi: 10.1177/03009858211005537. Epub 2021 May 27. Vet Pathol. 2021. PMID: 34039100 Review.
Humanization with CD34-positive hematopoietic stem cells in NOG-EXL mice results in improved long-term survival and less severe myeloid cell hyperactivation phenotype relative to NSG-SGM3 mice.
Willis E, Verrelle J, Banerjee E, Assenmacher CA, Tarrant JC, Skuli N, Jacobson ML, O'Rouke DM, Binder ZA, Radaelli E. Willis E, et al. Among authors: tarrant jc. Vet Pathol. 2024 Jan 10:3009858231222216. doi: 10.1177/03009858231222216. Online ahead of print. Vet Pathol. 2024. PMID: 38197423 Free article.
Lipid nanoparticle-encapsulated mRNA therapy corrects serum total bilirubin level in Crigler-Najjar syndrome mouse model.
Greig JA, Chorazeczewski JK, Chowdhary V, Smith MK, Jennis M, Tarrant JC, Buza EL, Coughlan K, Martini PGV, Wilson JM. Greig JA, et al. Among authors: tarrant jc. Mol Ther Methods Clin Dev. 2023 Feb 15;29:32-39. doi: 10.1016/j.omtm.2023.02.007. eCollection 2023 Jun 8. Mol Ther Methods Clin Dev. 2023. PMID: 36936447 Free PMC article.
13 results