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Lentiviral vector ALS20 yields high hemoglobin levels with low genomic integrations for treatment of beta-globinopathies.
Breda L, Ghiaccio V, Tanaka N, Jarocha D, Ikawa Y, Abdulmalik O, Dong A, Casu C, Raabe TD, Shan X, Danet-Desnoyers GA, Doto AM, Everett J, Bushman FD, Radaelli E, Assenmacher CA, Tarrant JC, Hoepp N, Kurita R, Nakamura Y, Guzikowski V, Smith-Whitley K, Kwiatkowski JL, Rivella S. Breda L, et al. Among authors: bushman fd. Mol Ther. 2021 Apr 7;29(4):1625-1638. doi: 10.1016/j.ymthe.2020.12.036. Epub 2021 Jan 29. Mol Ther. 2021. PMID: 33515514 Free PMC article.
Nondividing cells: a safer bet for integrating vectors?
Brady T, Bushman FD. Brady T, et al. Among authors: bushman fd. Mol Ther. 2011 Apr;19(4):640-1. doi: 10.1038/mt.2011.40. Mol Ther. 2011. PMID: 21455211 Free PMC article. No abstract available.
Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases.
Wilen CB, Wang J, Tilton JC, Miller JC, Kim KA, Rebar EJ, Sherrill-Mix SA, Patro SC, Secreto AJ, Jordan AP, Lee G, Kahn J, Aye PP, Bunnell BA, Lackner AA, Hoxie JA, Danet-Desnoyers GA, Bushman FD, Riley JL, Gregory PD, June CH, Holmes MC, Doms RW. Wilen CB, et al. Among authors: bushman fd. PLoS Pathog. 2011 Apr;7(4):e1002020. doi: 10.1371/journal.ppat.1002020. Epub 2011 Apr 14. PLoS Pathog. 2011. PMID: 21533216 Free PMC article.
Charting a clear path: the ASGCT Standardized Pathways Conference.
Kiem HP, Baum C, Bushman FD, Byrne BJ, Carter BJ, Cavagnaro J, Malech HL, Mendell JR, Naldini LM, Sorrentino BP, Williams DA, Flotte TR. Kiem HP, et al. Among authors: bushman fd. Mol Ther. 2014 Jul;22(7):1235-1238. doi: 10.1038/mt.2014.95. Mol Ther. 2014. PMID: 24981438 Free PMC article. No abstract available.
INSPIIRED: Quantification and Visualization Tools for Analyzing Integration Site Distributions.
Berry CC, Nobles C, Six E, Wu Y, Malani N, Sherman E, Dryga A, Everett JK, Male F, Bailey A, Bittinger K, Drake MJ, Caccavelli L, Bates P, Hacein-Bey-Abina S, Cavazzana M, Bushman FD. Berry CC, et al. Among authors: bushman fd. Mol Ther Methods Clin Dev. 2016 Dec 18;4:17-26. doi: 10.1016/j.omtm.2016.11.003. eCollection 2017 Mar 17. Mol Ther Methods Clin Dev. 2016. PMID: 28344988 Free PMC article.
403 results