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Steroid-resistant human inflammatory ILC2s are marked by CD45RO and elevated in type 2 respiratory diseases.
van der Ploeg EK, Golebski K, van Nimwegen M, Fergusson JR, Heesters BA, Martinez-Gonzalez I, Kradolfer CMA, van Tol S, Scicluna BP, de Bruijn MJW, de Boer GM, Tramper-Stranders GA, Braunstahl GJ, van IJcken WFJ, Nagtegaal AP, van Drunen CM, Fokkens WJ, Huylebroeck D, Spits H, Hendriks RW, Stadhouders R, Bal SM. van der Ploeg EK, et al. Among authors: scicluna bp. Sci Immunol. 2021 Jan 29;6(55):eabd3489. doi: 10.1126/sciimmunol.abd3489. Sci Immunol. 2021. PMID: 33514640
Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis.
Cheng SC, Scicluna BP, Arts RJ, Gresnigt MS, Lachmandas E, Giamarellos-Bourboulis EJ, Kox M, Manjeri GR, Wagenaars JA, Cremer OL, Leentjens J, van der Meer AJ, van de Veerdonk FL, Bonten MJ, Schultz MJ, Willems PH, Pickkers P, Joosten LA, van der Poll T, Netea MG. Cheng SC, et al. Among authors: scicluna bp. Nat Immunol. 2016 Apr;17(4):406-13. doi: 10.1038/ni.3398. Epub 2016 Mar 7. Nat Immunol. 2016. PMID: 26950237
HIVEP1 Is a Negative Regulator of NF-κB That Inhibits Systemic Inflammation in Sepsis.
Matsumoto H, Scicluna BP, Jim KK, Falahi F, Qin W, Gürkan B, Malmström E, Meijer MT, Butler JM, Khan HN, Takagi T, Ishii S, Schultz MJ, van de Beek D, de Vos AF, van 't Veer C, van der Poll T. Matsumoto H, et al. Among authors: scicluna bp. Front Immunol. 2021 Nov 5;12:744358. doi: 10.3389/fimmu.2021.744358. eCollection 2021. Front Immunol. 2021. PMID: 34804025 Free PMC article.
142 results