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Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes.
Comput Struct Biotechnol J. 2021 Jan 6;19:632-646. doi: 10.1016/j.csbj.2020.12.044. eCollection 2021.
Comput Struct Biotechnol J. 2021.
PMID: 33510867
Free PMC article.
Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors.
Martin-Malpartida P, Batet M, Kaczmarska Z, Freier R, Gomes T, Aragón E, Zou Y, Wang Q, Xi Q, Ruiz L, Vea A, Márquez JA, Massagué J, Macias MJ.
Martin-Malpartida P, et al. Among authors: freier r.
Nat Commun. 2017 Dec 12;8(1):2070. doi: 10.1038/s41467-017-02054-6.
Nat Commun. 2017.
PMID: 29234012
Free PMC article.
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Structures of the germline-specific Deadhead and thioredoxin T proteins from Drosophila melanogaster reveal unique features among thioredoxins.
Freier R, Aragón E, Bagiński B, Pluta R, Martin-Malpartida P, Ruiz L, Condeminas M, Gonzalez C, Macias MJ.
Freier R, et al.
IUCrJ. 2021 Feb 11;8(Pt 2):281-294. doi: 10.1107/S2052252521000221. eCollection 2021 Mar 1.
IUCrJ. 2021.
PMID: 33708404
Free PMC article.
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Crystal structure of the human odorant binding protein, OBPIIa.
Schiefner A, Freier R, Eichinger A, Skerra A.
Schiefner A, et al. Among authors: freier r.
Proteins. 2015 Jun;83(6):1180-4. doi: 10.1002/prot.24797. Epub 2015 Apr 4.
Proteins. 2015.
PMID: 25810031
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Protease recognition sites in Bet v 1a are cryptic, explaining its slow processing relevant to its allergenicity.
Freier R, Dall E, Brandstetter H.
Freier R, et al.
Sci Rep. 2015 Aug 3;5:12707. doi: 10.1038/srep12707.
Sci Rep. 2015.
PMID: 26235974
Free PMC article.
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Ligand binding modulates the structural dynamics and compactness of the major birch pollen allergen.
Grutsch S, Fuchs JE, Freier R, Kofler S, Bibi M, Asam C, Wallner M, Ferreira F, Brandstetter H, Liedl KR, Tollinger M.
Grutsch S, et al. Among authors: freier r.
Biophys J. 2014 Dec 16;107(12):2972-2981. doi: 10.1016/j.bpj.2014.10.062.
Biophys J. 2014.
PMID: 25517162
Free PMC article.
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Crystal structure of Pla l 1 reveals both structural similarity and allergenic divergence within the Ole e 1-like protein family.
Stemeseder T, Freier R, Wildner S, Fuchs JE, Briza P, Lang R, Batanero E, Lidholm J, Liedl KR, Campo P, Hawranek T, Villalba M, Brandstetter H, Ferreira F, Gadermaier G.
Stemeseder T, et al. Among authors: freier r.
J Allergy Clin Immunol. 2017 Jul;140(1):277-280. doi: 10.1016/j.jaci.2016.10.035. Epub 2016 Dec 10.
J Allergy Clin Immunol. 2017.
PMID: 27965108
Free PMC article.
No abstract available.
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Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen.
Machado Y, Freier R, Scheiblhofer S, Thalhamer T, Mayr M, Briza P, Grutsch S, Ahammer L, Fuchs JE, Wallnoefer HG, Isakovic A, Kohlbauer V, Hinterholzer A, Steiner M, Danzer M, Horejs-Hoeck J, Ferreira F, Liedl KR, Tollinger M, Lackner P, Johnson CM, Brandstetter H, Thalhamer J, Weiss R.
Machado Y, et al. Among authors: freier r.
J Allergy Clin Immunol. 2016 May;137(5):1525-34. doi: 10.1016/j.jaci.2015.09.026. Epub 2015 Nov 11.
J Allergy Clin Immunol. 2016.
PMID: 26559323
Free PMC article.
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