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The crystal structure of the green tea polyphenol (-)-epigallocatechin gallate-transthyretin complex reveals a novel binding site distinct from the thyroxine binding site.
Miyata M, Sato T, Kugimiya M, Sho M, Nakamura T, Ikemizu S, Chirifu M, Mizuguchi M, Nabeshima Y, Suwa Y, Morioka H, Arimori T, Suico MA, Shuto T, Sako Y, Momohara M, Koga T, Morino-Koga S, Yamagata Y, Kai H. Miyata M, et al. Among authors: chirifu m. Biochemistry. 2010 Jul 27;49(29):6104-14. doi: 10.1021/bi1004409. Biochemistry. 2010. PMID: 20565072
Crystallization and preliminary X-ray analysis of human MTH1 with a homogeneous N-terminus.
Koga Y, Inazato M, Nakamura T, Hashikawa C, Chirifu M, Michi A, Yamashita T, Toma S, Kuniyasu A, Ikemizu S, Nakabeppu Y, Yamagata Y. Koga Y, et al. Among authors: chirifu m. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jan 1;69(Pt 1):45-8. doi: 10.1107/S1744309112048002. Epub 2012 Dec 20. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 23295485 Free PMC article.
SIRT7 has a critical role in bone formation by regulating lysine acylation of SP7/Osterix.
Fukuda M, Yoshizawa T, Karim MF, Sobuz SU, Korogi W, Kobayasi D, Okanishi H, Tasaki M, Ono K, Sawa T, Sato Y, Chirifu M, Masuda T, Nakamura T, Tanoue H, Nakashima K, Kobashigawa Y, Morioka H, Bober E, Ohtsuki S, Yamagata Y, Ando Y, Oike Y, Araki N, Takeda S, Mizuta H, Yamagata K. Fukuda M, et al. Among authors: chirifu m. Nat Commun. 2018 Jul 19;9(1):2833. doi: 10.1038/s41467-018-05187-4. Nat Commun. 2018. PMID: 30026585 Free PMC article.
14 results