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XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer.
Ruan D, Peng J, Wang X, Ouyang Z, Zou Q, Yang Y, Chen F, Ge W, Wu H, Liu Z, Zhao Y, Zhao B, Zhang Q, Lai C, Fan N, Zhou Z, Liu Q, Li N, Jin Q, Shi H, Xie J, Song H, Yang X, Chen J, Wang K, Li X, Lai L. Ruan D, et al. Among authors: chen j, chen f. Stem Cell Reports. 2018 Feb 13;10(2):494-508. doi: 10.1016/j.stemcr.2017.12.015. Epub 2018 Jan 11. Stem Cell Reports. 2018. PMID: 29337117 Free PMC article.
Engineering CRISPR/Cpf1 with tRNA promotes genome editing capability in mammalian systems.
Wu H, Liu Q, Shi H, Xie J, Zhang Q, Ouyang Z, Li N, Yang Y, Liu Z, Zhao Y, Lai C, Ruan D, Peng J, Ge W, Chen F, Fan N, Jin Q, Liang Y, Lan T, Yang X, Wang X, Lei Z, Doevendans PA, Sluijter JPG, Wang K, Li X, Lai L. Wu H, et al. Among authors: chen f. Cell Mol Life Sci. 2018 Oct;75(19):3593-3607. doi: 10.1007/s00018-018-2810-3. Epub 2018 Apr 10. Cell Mol Life Sci. 2018. PMID: 29637228 Free PMC article.
Efficient base editing for multiple genes and loci in pigs using base editors.
Xie J, Ge W, Li N, Liu Q, Chen F, Yang X, Huang X, Ouyang Z, Zhang Q, Zhao Y, Liu Z, Gou S, Wu H, Lai C, Fan N, Jin Q, Shi H, Liang Y, Lan T, Quan L, Li X, Wang K, Lai L. Xie J, et al. Among authors: chen f. Nat Commun. 2019 Jun 28;10(1):2852. doi: 10.1038/s41467-019-10421-8. Nat Commun. 2019. PMID: 31253764 Free PMC article.
CRISPR/Cas9-Mediated Gene Correction in Newborn Rabbits with Hereditary Tyrosinemia Type I.
Li N, Gou S, Wang J, Zhang Q, Huang X, Xie J, Li L, Jin Q, Ouyang Z, Chen F, Ge W, Shi H, Liang Y, Zhuang Z, Zhao X, Lian M, Ye Y, Quan L, Wu H, Lai L, Wang K. Li N, et al. Among authors: chen f. Mol Ther. 2021 Mar 3;29(3):1001-1015. doi: 10.1016/j.ymthe.2020.11.023. Epub 2020 Nov 20. Mol Ther. 2021. PMID: 33221434 Free PMC article.
AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns.
Liang Y, Xie J, Zhang Q, Wang X, Gou S, Lin L, Chen T, Ge W, Zhuang Z, Lian M, Chen F, Li N, Ouyang Z, Lai C, Liu X, Li L, Ye Y, Wu H, Wang K, Lai L. Liang Y, et al. Among authors: chen t, chen f. Nucleic Acids Res. 2022 May 20;50(9):5384-5399. doi: 10.1093/nar/gkac353. Nucleic Acids Res. 2022. PMID: 35544322 Free PMC article.
Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression.
Jin Q, Yang X, Gou S, Liu X, Zhuang Z, Liang Y, Shi H, Huang J, Wu H, Zhao Y, Ouyang Z, Zhang Q, Liu Z, Chen F, Ge W, Xie J, Li N, Lai C, Zhao X, Wang J, Lian M, Li L, Quan L, Ye Y, Lai L, Wang K. Jin Q, et al. Among authors: chen f. Sci China Life Sci. 2022 Nov;65(11):2269-2286. doi: 10.1007/s11427-021-2088-1. Epub 2022 May 18. Sci China Life Sci. 2022. PMID: 35596888
Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors.
Chen F, Lian M, Ma B, Gou S, Luo X, Yang K, Shi H, Xie J, Ge W, Ouyang Z, Lai C, Li N, Zhang Q, Jin Q, Liang Y, Chen T, Wang J, Zhao X, Li L, Yu M, Ye Y, Wang K, Wu H, Lai L. Chen F, et al. Among authors: chen t. Commun Biol. 2022 Nov 2;5(1):1163. doi: 10.1038/s42003-022-04152-8. Commun Biol. 2022. PMID: 36323848 Free PMC article.
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