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The mitochondrial citrate carrier, SLC25A1, drives stemness and therapy resistance in non-small cell lung cancer.
Fernandez HR, Gadre SM, Tan M, Graham GT, Mosaoa R, Ongkeko MS, Kim KA, Riggins RB, Parasido E, Petrini I, Pacini S, Cheema A, Varghese R, Ressom HW, Zhang Y, Albanese C, Üren A, Paige M, Giaccone G, Avantaggiati ML. Fernandez HR, et al. Among authors: avantaggiati ml. Cell Death Differ. 2018 Jul;25(7):1239-1258. doi: 10.1038/s41418-018-0101-z. Epub 2018 Apr 12. Cell Death Differ. 2018. PMID: 29651165 Free PMC article.
Inhibition of the mitochondrial citrate carrier, Slc25a1, reverts steatosis, glucose intolerance, and inflammation in preclinical models of NAFLD/NASH.
Tan M, Mosaoa R, Graham GT, Kasprzyk-Pawelec A, Gadre S, Parasido E, Catalina-Rodriguez O, Foley P, Giaccone G, Cheema A, Kallakury B, Albanese C, Yi C, Avantaggiati ML. Tan M, et al. Among authors: avantaggiati ml. Cell Death Differ. 2020 Jul;27(7):2143-2157. doi: 10.1038/s41418-020-0491-6. Epub 2020 Jan 20. Cell Death Differ. 2020. PMID: 31959914 Free PMC article.
The SLC25A1-p53 mutant crosstalk.
Albanese C, Avantaggiati ML. Albanese C, et al. Among authors: avantaggiati ml. Aging (Albany NY). 2015 Aug;7(8):519-20. doi: 10.18632/aging.100785. Aging (Albany NY). 2015. PMID: 26298092 Free PMC article. No abstract available.
The mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis.
Catalina-Rodriguez O, Kolukula VK, Tomita Y, Preet A, Palmieri F, Wellstein A, Byers S, Giaccia AJ, Glasgow E, Albanese C, Avantaggiati ML. Catalina-Rodriguez O, et al. Among authors: avantaggiati ml. Oncotarget. 2012 Oct;3(10):1220-35. doi: 10.18632/oncotarget.714. Oncotarget. 2012. PMID: 23100451 Free PMC article.
Acetylation Increases EWS-FLI1 DNA Binding and Transcriptional Activity.
Schlottmann S, Erkizan HV, Barber-Rotenberg JS, Knights C, Cheema A, Uren A, Avantaggiati ML, Toretsky JA. Schlottmann S, et al. Among authors: avantaggiati ml. Front Oncol. 2012 Sep 7;2:107. doi: 10.3389/fonc.2012.00107. eCollection 2012. Front Oncol. 2012. PMID: 22973553 Free PMC article.
Reactivation of mutant p53 by a dietary-related compound phenethyl isothiocyanate inhibits tumor growth.
Aggarwal M, Saxena R, Sinclair E, Fu Y, Jacobs A, Dyba M, Wang X, Cruz I, Berry D, Kallakury B, Mueller SC, Agostino SD, Blandino G, Avantaggiati ML, Chung FL. Aggarwal M, et al. Among authors: avantaggiati ml. Cell Death Differ. 2016 Oct;23(10):1615-27. doi: 10.1038/cdd.2016.48. Epub 2016 Jun 3. Cell Death Differ. 2016. PMID: 27258787 Free PMC article.
75 results