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Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis.
Johnson BA, Xie X, Bailey AL, Kalveram B, Lokugamage KG, Muruato A, Zou J, Zhang X, Juelich T, Smith JK, Zhang L, Bopp N, Schindewolf C, Vu M, Vanderheiden A, Winkler ES, Swetnam D, Plante JA, Aguilar P, Plante KS, Popov V, Lee B, Weaver SC, Suthar MS, Routh AL, Ren P, Ku Z, An Z, Debbink K, Diamond MS, Shi PY, Freiberg AN, Menachery VD. Johnson BA, et al. Among authors: shi py. Nature. 2021 Mar;591(7849):293-299. doi: 10.1038/s41586-021-03237-4. Epub 2021 Jan 25. Nature. 2021. PMID: 33494095 Free PMC article.
Triaryl pyrazoline compound inhibits flavivirus RNA replication.
Puig-Basagoiti F, Tilgner M, Forshey BM, Philpott SM, Espina NG, Wentworth DE, Goebel SJ, Masters PS, Falgout B, Ren P, Ferguson DM, Shi PY. Puig-Basagoiti F, et al. Among authors: shi py. Antimicrob Agents Chemother. 2006 Apr;50(4):1320-9. doi: 10.1128/AAC.50.4.1320-1329.2006. Antimicrob Agents Chemother. 2006. PMID: 16569847 Free PMC article.
2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members.
Daffis S, Szretter KJ, Schriewer J, Li J, Youn S, Errett J, Lin TY, Schneller S, Zust R, Dong H, Thiel V, Sen GC, Fensterl V, Klimstra WB, Pierson TC, Buller RM, Gale M Jr, Shi PY, Diamond MS. Daffis S, et al. Among authors: shi py. Nature. 2010 Nov 18;468(7322):452-6. doi: 10.1038/nature09489. Nature. 2010. PMID: 21085181 Free PMC article.
Dimerization of flavivirus NS4B protein.
Zou J, Xie X, Lee le T, Chandrasekaran R, Reynaud A, Yap L, Wang QY, Dong H, Kang C, Yuan Z, Lescar J, Shi PY. Zou J, et al. Among authors: shi py. J Virol. 2014 Mar;88(6):3379-91. doi: 10.1128/JVI.02782-13. Epub 2014 Jan 3. J Virol. 2014. PMID: 24390334 Free PMC article.
Targeting dengue virus NS4B protein for drug discovery.
Xie X, Zou J, Wang QY, Shi PY. Xie X, et al. Among authors: shi py. Antiviral Res. 2015 Jun;118:39-45. doi: 10.1016/j.antiviral.2015.03.007. Epub 2015 Mar 19. Antiviral Res. 2015. PMID: 25796970 Review.
474 results