Lorenzana AO - Search Results

1

Discovery of PIPE-359, a Brain-Penetrant, Selective M₁ Receptor Antagonist with Robust Efficacy in Murine MOG-EAE.

Schrader TO, Xiong Y, Lorenzana AO, Broadhead A, Stebbins KJ, Poon MM, Baccei C, Lorrain DS. Schrader TO, et al. Among authors: lorenzana ao. ACS Med Chem Lett. 2020 Dec 24;12(1):155-161. doi: 10.1021/acsmedchemlett.0c00626. eCollection 2021 Jan 14. ACS Med Chem Lett. 2020. PMID: 33488977 Free PMC article.

2

Identification and In Vivo Evaluation of Myelination Agent PIPE-3297, a Selective Kappa Opioid Receptor Agonist Devoid of β-Arrestin-2 Recruitment Efficacy.

Schrader TO, Lorrain KI, Bagnol D, Edu GC, Broadhead A, Baccei C, Poon MM, Stebbins KJ, Xiong Y, Lorenzana AO, Chan JR, Green AJ, Lorrain DS, Chen A. Schrader TO, et al. Among authors: lorenzana ao. ACS Chem Neurosci. 2024 Feb 7;15(3):685-698. doi: 10.1021/acschemneuro.3c00807. Epub 2024 Jan 24. ACS Chem Neurosci. 2024. PMID: 38265210

3

Discovery of a brain penetrant small molecule antagonist targeting LPA1 receptors to reduce neuroinflammation and promote remyelination in multiple sclerosis.

Poon MM, Lorrain KI, Stebbins KJ, Edu GC, Broadhead AR, Lorenzana AO, Paulson BE, Baccei CS, Roppe JR, Schrader TO, Valdez LJ, Xiong Y, Chen AC, Lorrain DS. Poon MM, et al. Among authors: lorenzana ao. Sci Rep. 2024 May 8;14(1):10573. doi: 10.1038/s41598-024-61369-9. Sci Rep. 2024. PMID: 38719983 Free PMC article.

4

Transient demyelination increases the efficiency of retrograde AAV transduction.

Hollis ER 2nd, Jamshidi P, Lorenzana AO, Lee JK, Gray SJ, Samulski RJ, Zheng B, Tuszynski MH. Hollis ER 2nd, et al. Among authors: lorenzana ao. Mol Ther. 2010 Aug;18(8):1496-500. doi: 10.1038/mt.2010.97. Epub 2010 May 25. Mol Ther. 2010. PMID: 20502445 Free PMC article.

5

Effects of PTEN and Nogo Codeletion on Corticospinal Axon Sprouting and Regeneration in Mice.

Geoffroy CG, Lorenzana AO, Kwan JP, Lin K, Ghassemi O, Ma A, Xu N, Creger D, Liu K, He Z, Zheng B. Geoffroy CG, et al. Among authors: lorenzana ao. J Neurosci. 2015 Apr 22;35(16):6413-28. doi: 10.1523/JNEUROSCI.4013-14.2015. J Neurosci. 2015. PMID: 25904793 Free PMC article.

6

Understanding the axonal response to injury by in vivo imaging in the mouse spinal cord: A tale of two branches.

Zheng B, Lorenzana AO, Ma L. Zheng B, et al. Among authors: lorenzana ao. Exp Neurol. 2019 Aug;318:277-285. doi: 10.1016/j.expneurol.2019.04.008. Epub 2019 Apr 12. Exp Neurol. 2019. PMID: 30986398 Free PMC article. Review.

7

A surviving intact branch stabilizes remaining axon architecture after injury as revealed by in vivo imaging in the mouse spinal cord.

Lorenzana AO, Lee JK, Mui M, Chang A, Zheng B. Lorenzana AO, et al. Neuron. 2015 May 20;86(4):947-954. doi: 10.1016/j.neuron.2015.03.061. Epub 2015 Apr 30. Neuron. 2015. PMID: 25937174 Free PMC article.

8

Effect of age on kainate-induced seizure severity and cell death.

McCord MC, Lorenzana A, Bloom CS, Chancer ZO, Schauwecker PE. McCord MC, et al. Neuroscience. 2008 Jun 26;154(3):1143-53. doi: 10.1016/j.neuroscience.2008.03.082. Epub 2008 Apr 11. Neuroscience. 2008. PMID: 18479826 Free PMC article.

9

A quantitative trait locus on chromosome 18 is a critical determinant of excitotoxic cell death susceptibility.

Lorenzana A, Chancer Z, Schauwecker PE. Lorenzana A, et al. Eur J Neurosci. 2007 Apr;25(7):1998-2008. doi: 10.1111/j.1460-9568.2007.05443.x. Eur J Neurosci. 2007. PMID: 17439488

10

Variation in Galr1 expression determines susceptibility to exocitotoxin-induced cell death in mice.

Kong S, Lorenzana A, Deng Q, McNeill TH, Schauwecker PE. Kong S, et al. Genes Brain Behav. 2008 Jul;7(5):587-98. doi: 10.1111/j.1601-183X.2008.00395.x. Genes Brain Behav. 2008. PMID: 18363852 Free PMC article.

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