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T-ALL can evolve to oncogene independence.
Abdulla H, Vo A, Shields BJ, Davies TJ, Jackson JT, Alserihi R, Viney EM, Wong T, Yan F, Wong NC, Demoen L, Curtis DJ, Alexander WS, Van Vlierberghe P, Dickins RA, McCormack MP. Abdulla H, et al. Among authors: dickins ra. Leukemia. 2021 Aug;35(8):2205-2219. doi: 10.1038/s41375-021-01120-9. Epub 2021 Jan 22. Leukemia. 2021. PMID: 33483615
Stage-specific control of early B cell development by the transcription factor Ikaros.
Schwickert TA, Tagoh H, Gültekin S, Dakic A, Axelsson E, Minnich M, Ebert A, Werner B, Roth M, Cimmino L, Dickins RA, Zuber J, Jaritz M, Busslinger M. Schwickert TA, et al. Among authors: dickins ra. Nat Immunol. 2014 Mar;15(3):283-93. doi: 10.1038/ni.2828. Epub 2014 Feb 9. Nat Immunol. 2014. PMID: 24509509 Free PMC article.
PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia.
Pang SH, Minnich M, Gangatirkar P, Zheng Z, Ebert A, Song G, Dickins RA, Corcoran LM, Mullighan CG, Busslinger M, Huntington ND, Nutt SL, Carotta S. Pang SH, et al. Among authors: dickins ra. Leukemia. 2016 Jun;30(6):1375-87. doi: 10.1038/leu.2016.27. Epub 2016 Mar 2. Leukemia. 2016. PMID: 26932576 Free PMC article.
Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome.
Witkowski MT, Hu Y, Roberts KG, Boer JM, McKenzie MD, Liu GJ, Le Grice OD, Tremblay CS, Ghisi M, Willson TA, Horstmann MA, Aifantis I, Cimmino L, Frietze S, den Boer ML, Mullighan CG, Smyth GK, Dickins RA. Witkowski MT, et al. Among authors: dickins ra. J Exp Med. 2017 Mar 6;214(3):773-791. doi: 10.1084/jem.20160048. Epub 2017 Feb 11. J Exp Med. 2017. PMID: 28190000 Free PMC article.
The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1.
Carmichael CL, Wang J, Nguyen T, Kolawole O, Benyoucef A, De Mazière C, Milne AR, Samuel S, Gillinder K, Hediyeh-Zadeh S, Vo ANQ, Huang Y, Knezevic K, McInnes WRL, Shields BJ, Mitchell H, Ritchie ME, Lammens T, Lintermans B, Van Vlierberghe P, Wong NC, Haigh K, Thoms JAI, Toulmin E, Curtis DJ, Oxley EP, Dickins RA, Beck D, Perkins A, McCormack MP, Davis MJ, Berx G, Zuber J, Pimanda JE, Kile BT, Goossens S, Haigh JJ. Carmichael CL, et al. Among authors: dickins ra. Blood. 2020 Aug 20;136(8):957-973. doi: 10.1182/blood.2019002548. Blood. 2020. PMID: 32369597 Free PMC article.
Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia.
Van Thillo Q, De Bie J, Seneviratne JA, Demeyer S, Omari S, Balachandran A, Zhai V, Tam WL, Sweron B, Geerdens E, Gielen O, Provost S, Segers H, Boeckx N, Marshall GM, Cheung BB, Isobe K, Kato I, Takita J, Amos TG, Deveson IW, McCalmont H, Lock RB, Oxley EP, Garwood MM, Dickins RA, Uyttebroeck A, Carter DR, Cools J, de Bock CE. Van Thillo Q, et al. Among authors: dickins ra. Nat Commun. 2021 Jul 6;12(1):4164. doi: 10.1038/s41467-021-24442-9. Nat Commun. 2021. PMID: 34230493 Free PMC article.
Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia.
Churchman ML, Low J, Qu C, Paietta EM, Kasper LH, Chang Y, Payne-Turner D, Althoff MJ, Song G, Chen SC, Ma J, Rusch M, McGoldrick D, Edmonson M, Gupta P, Wang YD, Caufield W, Freeman B, Li L, Panetta JC, Baker S, Yang YL, Roberts KG, McCastlain K, Iacobucci I, Peters JL, Centonze VE, Notta F, Dobson SM, Zandi S, Dick JE, Janke L, Peng J, Kodali K, Pagala V, Min J, Mayasundari A, Williams RT, Willman CL, Rowe J, Luger S, Dickins RA, Guy RK, Chen T, Mullighan CG. Churchman ML, et al. Among authors: dickins ra. Cancer Cell. 2015 Sep 14;28(3):343-56. doi: 10.1016/j.ccell.2015.07.016. Epub 2015 Aug 27. Cancer Cell. 2015. PMID: 26321221 Free PMC article.
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