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849 results

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Loss of Parkinson's susceptibility gene LRRK2 promotes carcinogen-induced lung tumorigenesis.
Lebovitz C, Wretham N, Osooly M, Milne K, Dash T, Thornton S, Tessier-Cloutier B, Sathiyaseelan P, Bortnik S, Go NE, Halvorsen E, Cederberg RA, Chow N, Dos Santos N, Bennewith KL, Nelson BH, Bally MB, Lam WL, Gorski SM. Lebovitz C, et al. Among authors: thornton s. Sci Rep. 2021 Jan 22;11(1):2097. doi: 10.1038/s41598-021-81639-0. Sci Rep. 2021. PMID: 33483550 Free PMC article.
Profiling the immune landscape in mucinous ovarian carcinoma.
Meagher NS, Hamilton P, Milne K, Thornton S, Harris B, Weir A, Alsop J, Bisinoto C, Brenton JD, Brooks-Wilson A, Chiu DS, Cushing-Haugen KL, Fereday S, Garsed DW, Gayther SA, Gentry-Maharaj A, Gilks B, Jimenez-Linan M, Kennedy CJ, Le ND, Piskorz AM, Riggan MJ, Shah M, Singh N, Talhouk A, Widschwendter M, Bowtell DDL, Candido Dos Reis FJ, Cook LS, Fortner RT, García MJ, Harris HR, Huntsman DG, Karnezis AN, Köbel M, Menon U, Pharoah PDP, Doherty JA, Anglesio MS, Pike MC, Pearce CL, Friedlander ML, DeFazio A, Nelson BH, Ramus SJ. Meagher NS, et al. Among authors: thornton s. Gynecol Oncol. 2023 Jan;168:23-31. doi: 10.1016/j.ygyno.2022.10.022. Epub 2022 Nov 8. Gynecol Oncol. 2023. PMID: 36368129 Free PMC article.
The Prognostic Effect of Immune Cell Infiltration Depends on Molecular Subtype in Endometrioid Ovarian Carcinomas.
Heinze K, Cairns ES, Thornton S, Harris B, Milne K, Grube M, Meyer C, Karnezis AN, Fereday S, Garsed DW, Leung SCY, Chiu DS, Moubarak M, Harter P, Heitz F, McAlpine JN, DeFazio A, Bowtell DDL, Goode EL, Pike M, Ramus SJ, Pearce CL, Staebler A, Köbel M, Kommoss S, Talhouk A, Nelson BH, Anglesio MS. Heinze K, et al. Among authors: thornton s. Clin Cancer Res. 2023 Sep 1;29(17):3471-3483. doi: 10.1158/1078-0432.CCR-22-3815. Clin Cancer Res. 2023. PMID: 37339172 Free PMC article.
A tumor-restricted glycoform of podocalyxin is a highly selective marker of immunologically cold high-grade serous ovarian carcinoma.
Brassard J, Hughes MR, Dean P, Hernaez DC, Thornton S, Banville AC, Smazynski J, Warren M, Zhang K, Milne K, Gilks CB, Mes-Masson AM, Huntsman DG, Nelson BH, Roskelley CD, McNagny KM. Brassard J, et al. Among authors: thornton s. Front Oncol. 2023 Dec 21;13:1286754. doi: 10.3389/fonc.2023.1286754. eCollection 2023. Front Oncol. 2023. PMID: 38188285 Free PMC article.
Biallelic Dicer1 Mutations in the Gynecologic Tract of Mice Drive Lineage-Specific Development of DICER1 Syndrome-Associated Cancer.
Wang Y, Chen SY, Ta M, Senz J, Tao LV, Thornton S, Tamvada N, Yang W, Moscovitz Y, Li E, Guo J, Shen C, Douglas JM, Ei-Naggar AM, Kommoss FKF, Underhill TM, Singh N, Gilks CB, Morin GB, Huntsman DG. Wang Y, et al. Among authors: thornton s. Cancer Res. 2023 Nov 1;83(21):3517-3528. doi: 10.1158/0008-5472.CAN-22-3620. Cancer Res. 2023. PMID: 37494476
Aberrant gene activation in synovial sarcoma relies on SSX specificity and increased PRC1.1 stability.
Benabdallah NS, Dalal V, Scott RW, Marcous F, Sotiriou A, Kommoss FKF, Pejkovska A, Gaspar L, Wagner L, Sánchez-Rivera FJ, Ta M, Thornton S, Nielsen TO, Underhill TM, Banito A. Benabdallah NS, et al. Among authors: thornton s. Nat Struct Mol Biol. 2023 Nov;30(11):1640-1652. doi: 10.1038/s41594-023-01096-3. Epub 2023 Sep 21. Nat Struct Mol Biol. 2023. PMID: 37735617 Free PMC article.
849 results