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Loss of Parkinson's susceptibility gene LRRK2 promotes carcinogen-induced lung tumorigenesis.
Lebovitz C, Wretham N, Osooly M, Milne K, Dash T, Thornton S, Tessier-Cloutier B, Sathiyaseelan P, Bortnik S, Go NE, Halvorsen E, Cederberg RA, Chow N, Dos Santos N, Bennewith KL, Nelson BH, Bally MB, Lam WL, Gorski SM. Lebovitz C, et al. Among authors: bally mb. Sci Rep. 2021 Jan 22;11(1):2097. doi: 10.1038/s41598-021-81639-0. Sci Rep. 2021. PMID: 33483550 Free PMC article.
A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B.
Bosc D, Vezenkov L, Bortnik S, An J, Xu J, Choutka C, Hannigan AM, Kovacic S, Loo S, Clark PGK, Chen G, Guay-Ross RN, Yang K, Dragowska WH, Zhang F, Go NE, Leung A, Honson NS, Pfeifer TA, Gleave M, Bally M, Jones SJ, Gorski SM, Young RN. Bosc D, et al. Sci Rep. 2018 Aug 3;8(1):11653. doi: 10.1038/s41598-018-29900-x. Sci Rep. 2018. PMID: 30076329 Free PMC article.
Autophagy inhibition augments the anticancer effects of epirubicin treatment in anthracycline-sensitive and -resistant triple-negative breast cancer.
Chittaranjan S, Bortnik S, Dragowska WH, Xu J, Abeysundara N, Leung A, Go NE, DeVorkin L, Weppler SA, Gelmon K, Yapp DT, Bally MB, Gorski SM. Chittaranjan S, et al. Among authors: bally mb. Clin Cancer Res. 2014 Jun 15;20(12):3159-73. doi: 10.1158/1078-0432.CCR-13-2060. Epub 2014 Apr 10. Clin Cancer Res. 2014. PMID: 24721646
Identification of breast cancer cell subtypes sensitive to ATG4B inhibition.
Bortnik S, Choutka C, Horlings HM, Leung S, Baker JH, Lebovitz C, Dragowska WH, Go NE, Bally MB, Minchinton AI, Gelmon KA, Gorski SM. Bortnik S, et al. Among authors: bally mb. Oncotarget. 2016 Oct 11;7(41):66970-66988. doi: 10.18632/oncotarget.11408. Oncotarget. 2016. PMID: 27556700 Free PMC article.
Validating the use of a luciferase labeled breast cancer cell line, MDA435LCC6, as a means to monitor tumor progression and to assess the therapeutic activity of an established anticancer drug, docetaxel (Dt) alone or in combination with the ILK inhibitor, QLT0267.
Kalra J, Anantha M, Warburton C, Waterhouse D, Yan H, Yang YJ, Strut D, Osooly M, Masin D, Bally MB. Kalra J, et al. Among authors: bally mb. Cancer Biol Ther. 2011 May 1;11(9):826-38. doi: 10.4161/cbt.11.9.15183. Epub 2011 May 1. Cancer Biol Ther. 2011. PMID: 21358264 Free PMC article.
232 results