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Page 1
The Genomic Landscape of Actinic Keratosis.
Thomson J, Bewicke-Copley F, Anene CA, Gulati A, Nagano A, Purdie K, Inman GJ, Proby CM, Leigh IM, Harwood CA, Wang J. Thomson J, et al. J Invest Dermatol. 2021 Jul;141(7):1664-1674.e7. doi: 10.1016/j.jid.2020.12.024. Epub 2021 Jan 19. J Invest Dermatol. 2021. PMID: 33482222 Free PMC article.
Applications and analysis of targeted genomic sequencing in cancer studies.
Bewicke-Copley F, Arjun Kumar E, Palladino G, Korfi K, Wang J. Bewicke-Copley F, et al. Comput Struct Biotechnol J. 2019 Nov 7;17:1348-1359. doi: 10.1016/j.csbj.2019.10.004. eCollection 2019. Comput Struct Biotechnol J. 2019. PMID: 31762958 Free PMC article. Review.
The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants.
Rio-Machin A, Vulliamy T, Hug N, Walne A, Tawana K, Cardoso S, Ellison A, Pontikos N, Wang J, Tummala H, Al Seraihi AFH, Alnajar J, Bewicke-Copley F, Armes H, Barnett M, Bloor A, Bödör C, Bowen D, Fenaux P, Green A, Hallahan A, Hjorth-Hansen H, Hossain U, Killick S, Lawson S, Layton M, Male AM, Marsh J, Mehta P, Mous R, Nomdedéu JF, Owen C, Pavlu J, Payne EM, Protheroe RE, Preudhomme C, Pujol-Moix N, Renneville A, Russell N, Saggar A, Sciuccati G, Taussig D, Toze CL, Uyttebroeck A, Vandenberghe P, Schlegelberger B, Ripperger T, Steinemann D, Wu J, Mason J, Page P, Akiki S, Reay K, Cavenagh JD, Plagnol V, Caceres JF, Fitzgibbon J, Dokal I. Rio-Machin A, et al. Nat Commun. 2020 Feb 25;11(1):1044. doi: 10.1038/s41467-020-14829-5. Nat Commun. 2020. PMID: 32098966 Free PMC article.
A frameshift variant in specificity protein 1 triggers superactivation of Sp1-mediated transcription in familial bone marrow failure.
Tummala H, Walne AJ, Bewicke-Copley F, Ellison A, Pontikos N, Bridger MG, Rio-Machin A, Sidhu JK, Wang J, Hasle H, Fitzgibbon J, Vulliamy T, Dokal I. Tummala H, et al. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):17151-17155. doi: 10.1073/pnas.2002857117. Epub 2020 Jul 7. Proc Natl Acad Sci U S A. 2020. PMID: 32636268 Free PMC article.
Longitudinal expression profiling identifies a poor risk subset of patients with ABC-type diffuse large B-cell lymphoma.
Bewicke-Copley F, Korfi K, Araf S, Hodkinson B, Kumar E, Cummin T, Ashton-Key M, Barrans S, van Hoppe S, Burton C, Elshiekh M, Rule S, Crosbie N, Clear A, Calaminici M, Runge H, Hills RK, Scott DW, Rimsza LM, Menon G, Sha C, Davies JR, Nagano A, Davies A, Painter D, Smith A, Gribben J, Naresh KN, Westhead DR, Okosun J, Steele A, Hodson DJ, Balasubramanian S, Johnson P, Wang J, Fitzgibbon J. Bewicke-Copley F, et al. Blood Adv. 2023 Mar 14;7(5):845-855. doi: 10.1182/bloodadvances.2022007536. Blood Adv. 2023. PMID: 35947123 Free PMC article.
Transcriptomic analysis of cutaneous squamous cell carcinoma reveals a multigene prognostic signature associated with metastasis.
Wang J, Harwood CA, Bailey E, Bewicke-Copley F, Anene CA, Thomson J, Qamar MJ, Laban R, Nourse C, Schoenherr C, Treanor-Taylor M, Healy E, Lai C, Craig P, Moyes C, Rickaby W, Martin J, Proby C, Inman GJ, Leigh IM. Wang J, et al. Among authors: bewicke copley f. J Am Acad Dermatol. 2023 Dec;89(6):1159-1166. doi: 10.1016/j.jaad.2023.08.012. Epub 2023 Aug 14. J Am Acad Dermatol. 2023. PMID: 37586461 Free article.
Genetic heterogeneity highlighted by differential FDG-PET response in diffuse large B-cell lymphoma.
Araf S, Korfi K, Bewicke-Copley F, Wang J, Cogliatti S, Kumar E, Forrer F, Barrington SF, Graham TA, Scott DW, Rimsza LM, Davies A, Johnson P, Okosun J, Fitzgibbon J, Fehr M. Araf S, et al. Haematologica. 2020 Jun;105(6):318-321. doi: 10.3324/haematol.2019.242206. Epub 2020 Apr 9. Haematologica. 2020. PMID: 32273479 Free PMC article. No abstract available.
KDM5 inhibition offers a novel therapeutic strategy for the treatment of KMT2D mutant lymphomas.
Heward J, Konali L, D'Avola A, Close K, Yeomans A, Philpott M, Dunford J, Rahim T, Al Seraihi AF, Wang J, Korfi K, Araf S, Iqbal S, Bewicke-Copley F, Kumar E, Barisic D, Calaminici M, Clear A, Gribben J, Johnson P, Neve R, Cutillas P, Okosun J, Oppermann U, Melnick A, Packham G, Fitzgibbon J. Heward J, et al. Blood. 2021 Aug 5;138(5):370-381. doi: 10.1182/blood.2020008743. Blood. 2021. PMID: 33786580 Free PMC article.
21 results