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Novel antimycobacterial C-21 amide derivatives of the antibiotic fusidic acid: synthesis, pharmacological evaluation and rationalization of media-dependent activity using molecular docking studies in the binding site of human serum albumin.
Dziwornu GA, Kamunya S, Ntsabo T, Chibale K. Dziwornu GA, et al. Among authors: chibale k. Medchemcomm. 2019 Apr 18;10(6):961-969. doi: 10.1039/c9md00161a. eCollection 2019 Jun 1. Medchemcomm. 2019. PMID: 31303994 Free PMC article.
Semisynthetic Antimycobacterial C-3 Silicate and C-3/C-21 Ester Derivatives of Fusidic Acid: Pharmacological Evaluation and Stability Studies in Liver Microsomes, Rat Plasma, and Mycobacterium tuberculosis culture.
Njoroge M, Kaur G, Espinoza-Moraga M, Wasuna A, Dziwornu GA, Seldon R, Taylor D, Okombo J, Warner DF, Chibale K. Njoroge M, et al. Among authors: chibale k. ACS Infect Dis. 2019 Sep 13;5(9):1634-1644. doi: 10.1021/acsinfecdis.9b00208. Epub 2019 Jul 29. ACS Infect Dis. 2019. PMID: 31309823
278 results