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Myeloid lncRNA LOUP mediates opposing regulatory effects of RUNX1 and RUNX1-ETO in t(8;21) AML.
Trinh BQ, Ummarino S, Zhang Y, Ebralidze AK, Bassal MA, Nguyen TM, Heller G, Coffey R, Tenen DE, van der Kouwe E, Fabiani E, Gurnari C, Wu CS, Angarica VE, Yang H, Chen S, Zhang H, Thurm AR, Marchi F, Levantini E, Staber PB, Zhang P, Voso MT, Pandolfi PP, Kobayashi SS, Chai L, Di Ruscio A, Tenen DG. Trinh BQ, et al. Among authors: nguyen tm. Blood. 2021 Oct 14;138(15):1331-1344. doi: 10.1182/blood.2020007920. Blood. 2021. PMID: 33971010 Free PMC article.
Bifunctional modalities for repurposing protein function.
Modell AE, Lai S, Nguyen TM, Choudhary A. Modell AE, et al. Among authors: nguyen tm. Cell Chem Biol. 2021 Jul 15;28(7):1081-1089. doi: 10.1016/j.chembiol.2021.06.005. Cell Chem Biol. 2021. PMID: 34270935 Free article. Review.
CRISPR-based therapeutics: current challenges and future applications.
Modell AE, Lim D, Nguyen TM, Sreekanth V, Choudhary A. Modell AE, et al. Among authors: nguyen tm. Trends Pharmacol Sci. 2022 Feb;43(2):151-161. doi: 10.1016/j.tips.2021.10.012. Epub 2021 Dec 21. Trends Pharmacol Sci. 2022. PMID: 34952739 Free PMC article. Review.
Proteolysis-targeting chimeras with reduced off-targets.
Nguyen TM, Sreekanth V, Deb A, Kokkonda P, Tiwari PK, Donovan KA, Shoba V, Chaudhary SK, Mercer JAM, Lai S, Sadagopan A, Jan M, Fischer ES, Liu DR, Ebert BL, Choudhary A. Nguyen TM, et al. Nat Chem. 2024 Feb;16(2):218-228. doi: 10.1038/s41557-023-01379-8. Epub 2023 Dec 18. Nat Chem. 2024. PMID: 38110475 Free PMC article.
The SINEB1 element in the long non-coding RNA Malat1 is necessary for TDP-43 proteostasis.
Nguyen TM, Kabotyanski EB, Reineke LC, Shao J, Xiong F, Lee JH, Dubrulle J, Johnson H, Stossi F, Tsoi PS, Choi KJ, Ellis AG, Zhao N, Cao J, Adewunmi O, Ferreon JC, Ferreon ACM, Neilson JR, Mancini MA, Chen X, Kim J, Ma L, Li W, Rosen JM. Nguyen TM, et al. Nucleic Acids Res. 2020 Mar 18;48(5):2621-2642. doi: 10.1093/nar/gkz1176. Nucleic Acids Res. 2020. PMID: 31863590 Free PMC article.
Genome-wide identification and differential analysis of translational initiation.
Zhang P, He D, Xu Y, Hou J, Pan BF, Wang Y, Liu T, Davis CM, Ehli EA, Tan L, Zhou F, Hu J, Yu Y, Chen X, Nguyen TM, Rosen JM, Hawke DH, Ji Z, Chen Y. Zhang P, et al. Among authors: nguyen tm. Nat Commun. 2017 Nov 23;8(1):1749. doi: 10.1038/s41467-017-01981-8. Nat Commun. 2017. PMID: 29170441 Free PMC article.
889 results