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Exosomes in cancer development.
Curr Opin Genet Dev. 2021 Feb;66:83-92. doi: 10.1016/j.gde.2020.12.018. Epub 2021 Jan 18.
Curr Opin Genet Dev. 2021.
PMID: 33477017
Review.
Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation.
Stefanius K, Servage K, de Souza Santos M, Gray HF, Toombs JE, Chimalapati S, Kim MS, Malladi VS, Brekken R, Orth K.
Stefanius K, et al.
Elife. 2019 May 28;8:e40226. doi: 10.7554/eLife.40226.
Elife. 2019.
PMID: 31134894
Free PMC article.
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Proteomic Profiling of Small Extracellular Vesicles Secreted by Human Pancreatic Cancer Cells Implicated in Cellular Transformation.
Servage KA, Stefanius K, Gray HF, Orth K.
Servage KA, et al. Among authors: stefanius k.
Sci Rep. 2020 May 7;10(1):7713. doi: 10.1038/s41598-020-64718-6.
Sci Rep. 2020.
PMID: 32382024
Free PMC article.
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Fic-mediated AMPylation tempers the unfolded protein response during physiological stress.
Casey AK, Gray HF, Chimalapati S, Hernandez G, Moehlman AT, Stewart N, Fields HA, Gulen B, Servage KA, Stefanius K, Blevins A, Evers BM, Krämer H, Orth K.
Casey AK, et al. Among authors: stefanius k.
Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2208317119. doi: 10.1073/pnas.2208317119. Epub 2022 Aug 1.
Proc Natl Acad Sci U S A. 2022.
PMID: 35914137
Free PMC article.
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Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis.
Wang SS, Gu YF, Wolff N, Stefanius K, Christie A, Dey A, Hammer RE, Xie XJ, Rakheja D, Pedrosa I, Carroll T, McKay RM, Kapur P, Brugarolas J.
Wang SS, et al. Among authors: stefanius k.
Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16538-43. doi: 10.1073/pnas.1414789111. Epub 2014 Oct 30.
Proc Natl Acad Sci U S A. 2014.
PMID: 25359211
Free PMC article.
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Loss of PBRM1 and BAP1 expression is less common in non-clear cell renal cell carcinoma than in clear cell renal cell carcinoma.
Ho TH, Kapur P, Joseph RW, Serie DJ, Eckel-Passow JE, Parasramka M, Cheville JC, Wu KJ, Frenkel E, Rakheja D, Stefanius K, Brugarolas J, Parker AS.
Ho TH, et al. Among authors: stefanius k.
Urol Oncol. 2015 Jan;33(1):23.e9-23.e14. doi: 10.1016/j.urolonc.2014.10.014. Epub 2014 Nov 24.
Urol Oncol. 2015.
PMID: 25465300
Free PMC article.
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Downregulation of the hedgehog receptor PTCH1 in colorectal serrated adenocarcinomas is not caused by PTCH1 mutations.
Stefanius K, Kantola T, Tuomisto A, Vahteristo P, Karttunen TJ, Aaltonen LA, Mäkinen MJ, Karhu A.
Stefanius K, et al.
Virchows Arch. 2011 Feb;458(2):213-9. doi: 10.1007/s00428-010-1031-4. Epub 2011 Jan 14.
Virchows Arch. 2011.
PMID: 21234763
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Frequent mutations of KRAS in addition to BRAF in colorectal serrated adenocarcinoma.
Stefanius K, Ylitalo L, Tuomisto A, Kuivila R, Kantola T, Sirniö P, Karttunen TJ, Mäkinen MJ.
Stefanius K, et al.
Histopathology. 2011 Apr;58(5):679-92. doi: 10.1111/j.1365-2559.2011.03821.x. Epub 2011 Apr 4.
Histopathology. 2011.
PMID: 21457162
Free PMC article.
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