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Alphastatin-C a new inhibitor of endothelial cell activation is a pro-arteriogenic agent in vivo and retards B16-F10 melanoma growth in a preclinical model.
Ferreira AK, Cristofaro B, Menezes MC, de Oliveira AK, Tashima AK, de Melo RL, Silva CCF, Rodriguez MGP, Carvalho DCOS, de Azevedo RA, Junior PLS, Mambelli LI, Portaro FV, Pardanaud L, Eichmann A, Sant'Anna OA, Faria M. Ferreira AK, et al. Among authors: de azevedo ra. Oncotarget. 2020 Dec 22;11(51):4770-4787. doi: 10.18632/oncotarget.27839. eCollection 2020 Dec 22. Oncotarget. 2020. PMID: 33473260 Free PMC article.
Edelfosine: An Antitumor Drug Prototype.
Teixeira SF, Rodrigues CP, Costa CJS, Pettinati TN, de Azevedo RA, Mambelli LI, Jorge SD, Ramos RN, Ferro ES, Barbuto JAM, Ferreira AK. Teixeira SF, et al. Among authors: de azevedo ra. Anticancer Agents Med Chem. 2018;18(6):865-874. doi: 10.2174/1871520618666180105165431. Anticancer Agents Med Chem. 2018. PMID: 29308743
Mastoparan induces apoptosis in B16F10-Nex2 melanoma cells via the intrinsic mitochondrial pathway and displays antitumor activity in vivo.
de Azevedo RA, Figueiredo CR, Ferreira AK, Matsuo AL, Massaoka MH, Girola N, Auada AV, Farias CF, Pasqualoto KF, Rodrigues CP, Barbuto JA, Levy D, Bydlowski SP, de Sá-Junior PL, Travassos LR, Lebrun I. de Azevedo RA, et al. Among authors: de sa junior pl. Peptides. 2015 Jun;68:113-9. doi: 10.1016/j.peptides.2014.09.024. Epub 2014 Oct 14. Peptides. 2015. PMID: 25305549
RPF151, a novel capsaicin-like analogue: in vitro studies and in vivo preclinical antitumor evaluation in a breast cancer model.
Ferreira AK, Tavares MT, Pasqualoto KF, de Azevedo RA, Teixeira SF, Ferreira-Junior WA, Bertin AM, de-Sá-Junior PL, Barbuto JA, Figueiredo CR, Cury Y, Damião MC, Parise-Filho R. Ferreira AK, et al. Among authors: de sa junior pl, de azevedo ra. Tumour Biol. 2015 Sep;36(9):7251-67. doi: 10.1007/s13277-015-3441-z. Epub 2015 Apr 20. Tumour Biol. 2015. PMID: 25894379
RPF101, a new capsaicin-like analogue, disrupts the microtubule network accompanied by arrest in the G2/M phase, inducing apoptosis and mitotic catastrophe in the MCF-7 breast cancer cells.
de-Sá-Júnior PL, Pasqualoto KF, Ferreira AK, Tavares MT, Damião MC, de Azevedo RA, Câmara DA, Pereira A, de Souza DM, Parise Filho R. de-Sá-Júnior PL, et al. Among authors: de azevedo ra, de souza dm. Toxicol Appl Pharmacol. 2013 Feb 1;266(3):385-98. doi: 10.1016/j.taap.2012.11.029. Epub 2012 Dec 10. Toxicol Appl Pharmacol. 2013. PMID: 23238560
Designing and exploring active N'-[(5-nitrofuran-2-yl) methylene] substituted hydrazides against three Trypanosoma cruzi strains more prevalent in Chagas disease patients.
Palace-Berl F, Pasqualoto KF, Jorge SD, Zingales B, Zorzi RR, Silva MN, Ferreira AK, de Azevedo RA, Teixeira SF, Tavares LC. Palace-Berl F, et al. Among authors: de azevedo ra. Eur J Med Chem. 2015;96:330-9. doi: 10.1016/j.ejmech.2015.03.066. Epub 2015 Apr 1. Eur J Med Chem. 2015. PMID: 25899337
Cytotoxic effects of dillapiole on MDA-MB-231 cells involve the induction of apoptosis through the mitochondrial pathway by inducing an oxidative stress while altering the cytoskeleton network.
Ferreira AK, de-Sá-Júnior PL, Pasqualoto KF, de Azevedo RA, Câmara DA, Costa AS, Figueiredo CR, Matsuo AL, Massaoka MH, Auada AV, Lebrun I, Damião MC, Tavares MT, Magri FM, Kerkis I, Parise Filho R. Ferreira AK, et al. Among authors: de sa junior pl, de azevedo ra. Biochimie. 2014 Apr;99:195-207. doi: 10.1016/j.biochi.2013.12.008. Epub 2013 Dec 16. Biochimie. 2014. PMID: 24355203
37 results