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Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications.
Kearney KJ, Pechlivani N, King R, Tiede C, Phoenix F, Cheah R, Macrae FL, Simmons KJ, Manfield IW, Smith KA, Spurgeon BEJ, Naseem KM, Ariens RAS, McPherson MJ, Tomlinson DC, Ajjan RA. Kearney KJ, et al. Among authors: manfield iw. Blood. 2019 Mar 14;133(11):1233-1244. doi: 10.1182/blood-2018-06-856195. Epub 2018 Dec 13. Blood. 2019. PMID: 30545831 Free PMC article.
A Comparative Assessment Study of Known Small-molecule GPVI Modulators.
Foster H, Wilson C, Gauer JS, Xu RG, Howard MJ, Manfield IW, Ariëns R, Naseem K, Vidler LR, Philippou H, Foster R. Foster H, et al. Among authors: manfield iw. ACS Med Chem Lett. 2022 Jan 20;13(2):171-181. doi: 10.1021/acsmedchemlett.1c00414. eCollection 2022 Feb 10. ACS Med Chem Lett. 2022. PMID: 35178172 Free PMC article.
Direct Evidence for Packaging Signal-Mediated Assembly of Bacteriophage MS2.
Rolfsson Ó, Middleton S, Manfield IW, White SJ, Fan B, Vaughan R, Ranson NA, Dykeman E, Twarock R, Ford J, Kao CC, Stockley PG. Rolfsson Ó, et al. Among authors: manfield iw. J Mol Biol. 2016 Jan 29;428(2 Pt B):431-48. doi: 10.1016/j.jmb.2015.11.014. Epub 2015 Dec 1. J Mol Biol. 2016. PMID: 26608810 Free PMC article.
Affimer proteins are versatile and renewable affinity reagents.
Tiede C, Bedford R, Heseltine SJ, Smith G, Wijetunga I, Ross R, AlQallaf D, Roberts AP, Balls A, Curd A, Hughes RE, Martin H, Needham SR, Zanetti-Domingues LC, Sadigh Y, Peacock TP, Tang AA, Gibson N, Kyle H, Platt GW, Ingram N, Taylor T, Coletta LP, Manfield I, Knowles M, Bell S, Esteves F, Maqbool A, Prasad RK, Drinkhill M, Bon RS, Patel V, Goodchild SA, Martin-Fernandez M, Owens RJ, Nettleship JE, Webb ME, Harrison M, Lippiat JD, Ponnambalam S, Peckham M, Smith A, Ferrigno PK, Johnson M, McPherson MJ, Tomlinson DC. Tiede C, et al. Elife. 2017 Jun 27;6:e24903. doi: 10.7554/eLife.24903. Elife. 2017. PMID: 28654419 Free PMC article.
Trivalent Gd-DOTA reagents for modification of proteins.
Fisher MJ, Williamson DJ, Burslem GM, Plante JP, Manfield IW, Tiede C, Ault JR, Stockley PG, Plein S, Maqbool A, Tomlinson DC, Foster R, Warriner SL, Bon RS. Fisher MJ, et al. Among authors: manfield iw. RSC Adv. 2015 Dec 9;5(116):96194-96200. doi: 10.1039/c5ra20359g. Epub 2015 Nov 11. RSC Adv. 2015. PMID: 27019702 Free PMC article.
Arabidopsis PEX19 is a dimeric protein that binds the peroxin PEX10.
Hadden DA, Phillipson BA, Johnston KA, Brown LA, Manfield IW, El-Shami M, Sparkes IA, Baker A. Hadden DA, et al. Among authors: manfield iw. Mol Membr Biol. 2006 Jul-Aug;23(4):325-36. doi: 10.1080/09687860600738221. Mol Membr Biol. 2006. PMID: 16923726 Free article.
49 results