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Positive epistasis between disease-causing missense mutations and silent polymorphism with effect on mRNA translation velocity.
Rauscher R, Bampi GB, Guevara-Ferrer M, Santos LA, Joshi D, Mark D, Strug LJ, Rommens JM, Ballmann M, Sorscher EJ, Oliver KE, Ignatova Z. Rauscher R, et al. Among authors: santos la. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2010612118. doi: 10.1073/pnas.2010612118. Proc Natl Acad Sci U S A. 2021. PMID: 33468668 Free PMC article.
Engineered tRNAs suppress nonsense mutations in cells and in vivo.
Albers S, Allen EC, Bharti N, Davyt M, Joshi D, Perez-Garcia CG, Santos L, Mukthavaram R, Delgado-Toscano MA, Molina B, Kuakini K, Alayyoubi M, Park KJ, Acharya G, Gonzalez JA, Sagi A, Birket SE, Tearney GJ, Rowe SM, Manfredi C, Hong JS, Tachikawa K, Karmali P, Matsuda D, Sorscher EJ, Chivukula P, Ignatova Z. Albers S, et al. Nature. 2023 Jun;618(7966):842-848. doi: 10.1038/s41586-023-06133-1. Epub 2023 May 31. Nature. 2023. PMID: 37258671 Free PMC article.
N6-methyladenosine in 5' UTR does not promote translation initiation.
Guca E, Alarcon R, Palo MZ, Santos L, Alonso-Gil S, Davyt M, de Lima LHF, Boissier F, Das S, Zagrovic B, Puglisi JD, Hashem Y, Ignatova Z. Guca E, et al. Mol Cell. 2024 Feb 1;84(3):584-595.e6. doi: 10.1016/j.molcel.2023.12.028. Epub 2024 Jan 19. Mol Cell. 2024. PMID: 38244546 Free article.
tRNA overexpression rescues peripheral neuropathy caused by mutations in tRNA synthetase.
Zuko A, Mallik M, Thompson R, Spaulding EL, Wienand AR, Been M, Tadenev ALD, van Bakel N, Sijlmans C, Santos LA, Bussmann J, Catinozzi M, Das S, Kulshrestha D, Burgess RW, Ignatova Z, Storkebaum E. Zuko A, et al. Among authors: santos la. Science. 2021 Sep 3;373(6559):1161-1166. doi: 10.1126/science.abb3356. Epub 2021 Sep 1. Science. 2021. PMID: 34516840 Free PMC article.
The incidence of osteoradionecrosis of the jaws in oral cavity cancer patients treated with intensity-modulated radiotherapy: a systematic review and meta-analysis.
de Almeida-Silva LA, Lupp JDS, Sobral-Silva LA, Dos Santos LAR, Marques TO, da Silva DBR, Caneppele TMF, Bianchi-de-Moraes M. de Almeida-Silva LA, et al. Among authors: dos santos lar. Oral Surg Oral Med Oral Pathol Oral Radiol. 2024 Apr 18:S2212-4403(24)00162-7. doi: 10.1016/j.oooo.2024.04.008. Online ahead of print. Oral Surg Oral Med Oral Pathol Oral Radiol. 2024. PMID: 38772792 Review.
392 results