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Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2.
Gyimesi M, Rauscher AÁ, Suthar SK, Hamow KÁ, Oravecz K, Lőrincz I, Borhegyi Z, Déri MT, Kiss ÁF, Monostory K, Szabó PT, Nag S, Tomasic I, Krans J, Tierney PJ, Kovács M, Kornya L, Málnási-Csizmadia A. Gyimesi M, et al. Among authors: oravecz k. J Pharmacol Exp Ther. 2021 Mar;376(3):358-373. doi: 10.1124/jpet.120.000167. Epub 2021 Jan 19. J Pharmacol Exp Ther. 2021. PMID: 33468641
Inotropic effect of NCX inhibition depends on the relative activity of the reverse NCX assessed by a novel inhibitor ORM-10962 on canine ventricular myocytes.
Oravecz K, Kormos A, Gruber A, Márton Z, Kohajda Z, Mirzaei L, Jost N, Levijoki J, Pollesello P, Koskelainen T, Otsomaa L, Tóth A, Papp JG, Nánási PP, Antoons G, Varró A, Acsai K, Nagy N. Oravecz K, et al. Eur J Pharmacol. 2018 Jan 5;818:278-286. doi: 10.1016/j.ejphar.2017.10.039. Epub 2017 Oct 21. Eur J Pharmacol. 2018. PMID: 29066415 Free article.
The investigation of the cellular electrophysiological and antiarrhythmic effects of a novel selective sodium-calcium exchanger inhibitor, GYKB-6635, in canine and guinea-pig hearts.
Geramipour A, Kohajda Z, Corici C, Prorok J, Szakonyi Z, Oravecz K, Márton Z, Nagy N, Tóth A, Acsai K, Virág L, Varró A, Jost N. Geramipour A, et al. Among authors: oravecz k. Can J Physiol Pharmacol. 2016 Oct;94(10):1090-1101. doi: 10.1139/cjpp-2015-0566. Epub 2016 Jul 1. Can J Physiol Pharmacol. 2016. PMID: 27508313
Increased Ca2+ content of the sarcoplasmic reticulum provides arrhythmogenic trigger source in swimming-induced rat athlete's heart model.
Gazdag P, Oravecz K, Acsai K, Demeter-Haludka V, Ördög B, Szlovák J, Kohajda Z, Polyák A, Barta BA, Oláh A, Radovits T, Merkely B, Papp JG, Baczkó I, Varró A, Nagy N, Prorok J. Gazdag P, et al. Among authors: oravecz k. Sci Rep. 2020 Nov 11;10(1):19596. doi: 10.1038/s41598-020-76496-2. Sci Rep. 2020. PMID: 33177643 Free PMC article.
Author Correction: Increased Ca2+ content of the sarcoplasmic reticulum provides arrhythmogenic trigger source in swimming-induced rat athlete's heart model.
Gazdag P, Oravecz K, Acsai K, Demeter-Haludka V, Ördög B, Szlovák J, Kohajda Z, Polyák A, Barta BA, Oláh A, Radovits T, Merkely B, Papp JG, Baczkó I, Varró A, Nagy N, Prorok J. Gazdag P, et al. Among authors: oravecz k. Sci Rep. 2021 Jun 4;11(1):12249. doi: 10.1038/s41598-021-91695-1. Sci Rep. 2021. PMID: 34088962 Free PMC article. No abstract available.
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