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Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice.
Dufies O, Doye A, Courjon J, Torre C, Michel G, Loubatier C, Jacquel A, Chaintreuil P, Majoor A, Guinamard RR, Gallerand A, Saavedra PHV, Verhoeyen E, Rey A, Marchetti S, Ruimy R, Czerucka D, Lamkanfi M, Py BF, Munro P, Visvikis O, Boyer L. Dufies O, et al. Among authors: jacquel a. Nat Microbiol. 2021 Mar;6(3):401-412. doi: 10.1038/s41564-020-00832-5. Epub 2021 Jan 11. Nat Microbiol. 2021. PMID: 33432150 Free PMC article.
Escherichia coli α-hemolysin counteracts the anti-virulence innate immune response triggered by the Rho GTPase activating toxin CNF1 during bacteremia.
Diabate M, Munro P, Garcia E, Jacquel A, Michel G, Obba S, Goncalves D, Luci C, Marchetti S, Demon D, Degos C, Bechah Y, Mege JL, Lamkanfi M, Auberger P, Gorvel JP, Stuart LM, Landraud L, Lemichez E, Boyer L. Diabate M, et al. Among authors: jacquel a. PLoS Pathog. 2015 Mar 17;11(3):e1004732. doi: 10.1371/journal.ppat.1004732. eCollection 2015 Mar. PLoS Pathog. 2015. PMID: 25781937 Free PMC article.
The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML.
Obba S, Hizir Z, Boyer L, Selimoglu-Buet D, Pfeifer A, Michel G, Hamouda MA, Gonçalvès D, Cerezo M, Marchetti S, Rocchi S, Droin N, Cluzeau T, Robert G, Luciano F, Robaye B, Foretz M, Viollet B, Legros L, Solary E, Auberger P, Jacquel A. Obba S, et al. Among authors: jacquel a. Autophagy. 2015;11(7):1114-29. doi: 10.1080/15548627.2015.1034406. Autophagy. 2015. PMID: 26029847 Free PMC article.
IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential.
Boulakirba S, Pfeifer A, Mhaidly R, Obba S, Goulard M, Schmitt T, Chaintreuil P, Calleja A, Furstoss N, Orange F, Lacas-Gervais S, Boyer L, Marchetti S, Verhoeyen E, Luciano F, Robert G, Auberger P, Jacquel A. Boulakirba S, et al. Among authors: jacquel a. Sci Rep. 2018 Jan 10;8(1):256. doi: 10.1038/s41598-017-18433-4. Sci Rep. 2018. PMID: 29321503 Free PMC article.
The oncogenic tyrosine kinase Lyn impairs the pro-apoptotic function of Bim.
Aira LE, Villa E, Colosetti P, Gamas P, Signetti L, Obba S, Proics E, Gautier F, Bailly-Maitre B, Jacquel A, Robert G, Luciano F, Juin PP, Ricci JE, Auberger P, Marchetti S. Aira LE, et al. Among authors: jacquel a. Oncogene. 2018 Apr;37(16):2122-2136. doi: 10.1038/s41388-017-0112-0. Epub 2018 Feb 2. Oncogene. 2018. PMID: 29391601
Caspase 1/11 Deficiency or Pharmacological Inhibition Mitigates Psoriasis-Like Phenotype in Mice.
Aira LE, Gonçalves D, Bossowski JP, Rubio-Patiño C, Chiche J, Paul-Bellon R, Mondragón L, Gesson M, Lecucq-Ottavi P, Obba S, Colosetti P, Luciano F, Bailly-Maitre B, Boyer L, Jacquel A, Robert G, Ricci JE, Ortonne JP, Passeron T, Lacour JP, Auberger P, Marchetti S. Aira LE, et al. Among authors: jacquel a. J Invest Dermatol. 2019 Jun;139(6):1306-1317. doi: 10.1016/j.jid.2018.11.031. Epub 2018 Dec 17. J Invest Dermatol. 2019. PMID: 30571969 Free article.
ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms.
Viaud M, Abdel-Wahab O, Gall J, Ivanov S, Guinamard R, Sore S, Merlin J, Ayrault M, Guilbaud E, Jacquel A, Auberger P, Wang N, Levine RL, Tall AR, Yvan-Charvet L. Viaud M, et al. Among authors: jacquel a. Cell Rep. 2020 Mar 10;30(10):3397-3410.e5. doi: 10.1016/j.celrep.2020.02.056. Cell Rep. 2020. PMID: 32160545 Free PMC article.
Heterogeneous NLRP3 inflammasome signature in circulating myeloid cells as a biomarker of COVID-19 severity.
Courjon J, Dufies O, Robert A, Bailly L, Torre C, Chirio D, Contenti J, Vitale S, Loubatier C, Doye A, Pomares-Estran C, Gonfrier G, Lotte R, Munro P, Visvikis O, Dellamonica J, Giordanengo V, Carles M, Yvan-Charvet L, Ivanov S, Auberger P, Jacquel A, Boyer L. Courjon J, et al. Among authors: jacquel a. Blood Adv. 2021 Mar 9;5(5):1523-1534. doi: 10.1182/bloodadvances.2020003918. Blood Adv. 2021. PMID: 33683342 Free PMC article.
Reprogramming monocyte-derived macrophages through caspase inhibition.
Chaintreuil P, Laplane L, Esnault F, Ghesquier V, Savy C, Furstoss N, Arcangeli ML, Cluzeau T, Robert G, Droin N, Solary E, Auberger P, Jacquel A. Chaintreuil P, et al. Among authors: jacquel a. Oncoimmunology. 2021 Dec 30;11(1):2015859. doi: 10.1080/2162402X.2021.2015859. eCollection 2022. Oncoimmunology. 2021. PMID: 35251769 Free PMC article.
93 results