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Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo.
Dominguez-Meijide A, Parrales V, Vasili E, González-Lizárraga F, König A, Lázaro DF, Lannuzel A, Haik S, Del Bel E, Chehín R, Raisman-Vozari R, Michel PP, Bizat N, Outeiro TF. Dominguez-Meijide A, et al. Among authors: michel pp. Neurobiol Dis. 2021 Apr;151:105256. doi: 10.1016/j.nbd.2021.105256. Epub 2021 Jan 8. Neurobiol Dis. 2021. PMID: 33429042 Free article.
The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy.
Höglinger GU, Lannuzel A, Khondiker ME, Michel PP, Duyckaerts C, Féger J, Champy P, Prigent A, Medja F, Lombes A, Oertel WH, Ruberg M, Hirsch EC. Höglinger GU, et al. Among authors: michel pp. J Neurochem. 2005 Nov;95(4):930-9. doi: 10.1111/j.1471-4159.2005.03493.x. Epub 2005 Aug 10. J Neurochem. 2005. PMID: 16219024 Free article.
Annonacin, a natural mitochondrial complex I inhibitor, causes tau pathology in cultured neurons.
Escobar-Khondiker M, Höllerhage M, Muriel MP, Champy P, Bach A, Depienne C, Respondek G, Yamada ES, Lannuzel A, Yagi T, Hirsch EC, Oertel WH, Jacob R, Michel PP, Ruberg M, Höglinger GU. Escobar-Khondiker M, et al. Among authors: michel pp. J Neurosci. 2007 Jul 18;27(29):7827-37. doi: 10.1523/JNEUROSCI.1644-07.2007. J Neurosci. 2007. PMID: 17634376 Free PMC article.
129 results