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CTLA-4 blockade and interferon-α induce proinflammatory transcriptional changes in the tumor immune landscape that correlate with pathologic response in melanoma.
Khunger A, Piazza E, Warren S, Smith TH, Ren X, White A, Elliott N, Cesano A, Beechem JM, Kirkwood JM, Tarhini AA. Khunger A, et al. Among authors: cesano a. PLoS One. 2021 Jan 11;16(1):e0245287. doi: 10.1371/journal.pone.0245287. eCollection 2021. PLoS One. 2021. PMID: 33428680 Free PMC article. Clinical Trial.
The tumor inflammation signature (TIS) is associated with anti-PD-1 treatment benefit in the CERTIM pan-cancer cohort.
Damotte D, Warren S, Arrondeau J, Boudou-Rouquette P, Mansuet-Lupo A, Biton J, Ouakrim H, Alifano M, Gervais C, Bellesoeur A, Kramkimel N, Tlemsani C, Burroni B, Duche A, Letourneur F, Si H, Halpin R, Creasy T, Herbst R, Ren X, Morel P, Cesano A, Goldwasser F, Leroy K. Damotte D, et al. Among authors: cesano a. J Transl Med. 2019 Nov 4;17(1):357. doi: 10.1186/s12967-019-2100-3. J Transl Med. 2019. PMID: 31684954 Free PMC article.
Immune landscapes predict chemotherapy resistance and immunotherapy response in acute myeloid leukemia.
Vadakekolathu J, Minden MD, Hood T, Church SE, Reeder S, Altmann H, Sullivan AH, Viboch EJ, Patel T, Ibrahimova N, Warren SE, Arruda A, Liang Y, Smith TH, Foulds GA, Bailey MD, Gowen-MacDonald J, Muth J, Schmitz M, Cesano A, Pockley AG, Valk PJM, Löwenberg B, Bornhäuser M, Tasian SK, Rettig MP, Davidson-Moncada JK, DiPersio JF, Rutella S. Vadakekolathu J, et al. Among authors: cesano a. Sci Transl Med. 2020 Jun 3;12(546):eaaz0463. doi: 10.1126/scitranslmed.aaz0463. Sci Transl Med. 2020. PMID: 32493790 Free PMC article.
Society for Immunotherapy of Cancer clinical and biomarkers data sharing resource document: Volume II-practical challenges.
Cesano A, Cannarile MA, Gnjatic S, Gomes B, Guinney J, Karanikas V, Karkada M, Kirkwood JM, Kotlan B, Masucci GV, Meeusen E, Monette A, Naing A, Thorsson V, Tschernia N, Wang E, Wells DK, Wyant TL, Rutella S. Cesano A, et al. J Immunother Cancer. 2020 Dec;8(2):e001472. doi: 10.1136/jitc-2020-001472. J Immunother Cancer. 2020. PMID: 33323463 Free PMC article.
131 results