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CTLA-4 blockade and interferon-α induce proinflammatory transcriptional changes in the tumor immune landscape that correlate with pathologic response in melanoma.
Khunger A, Piazza E, Warren S, Smith TH, Ren X, White A, Elliott N, Cesano A, Beechem JM, Kirkwood JM, Tarhini AA. Khunger A, et al. Among authors: beechem jm. PLoS One. 2021 Jan 11;16(1):e0245287. doi: 10.1371/journal.pone.0245287. eCollection 2021. PLoS One. 2021. PMID: 33428680 Free PMC article. Clinical Trial.
Gene expression markers of Tumor Infiltrating Leukocytes.
Danaher P, Warren S, Dennis L, D'Amico L, White A, Disis ML, Geller MA, Odunsi K, Beechem J, Fling SP. Danaher P, et al. J Immunother Cancer. 2017 Feb 21;5:18. doi: 10.1186/s40425-017-0215-8. eCollection 2017. J Immunother Cancer. 2017. PMID: 28239471 Free PMC article.
A case report of clonal EBV-like memory CD4+ T cell activation in fatal checkpoint inhibitor-induced encephalitis.
Johnson DB, McDonnell WJ, Gonzalez-Ericsson PI, Al-Rohil RN, Mobley BC, Salem JE, Wang DY, Sanchez V, Wang Y, Chastain CA, Barker K, Liang Y, Warren S, Beechem JM, Menzies AM, Tio M, Long GV, Cohen JV, Guidon AC, O'Hare M, Chandra S, Chowdhary A, Lebrun-Vignes B, Goldinger SM, Rushing EJ, Buchbinder EI, Mallal SA, Shi C, Xu Y, Moslehi JJ, Sanders ME, Sosman JA, Balko JM. Johnson DB, et al. Among authors: beechem jm. Nat Med. 2019 Aug;25(8):1243-1250. doi: 10.1038/s41591-019-0523-2. Epub 2019 Jul 22. Nat Med. 2019. PMID: 31332390 Free PMC article.
Multiplex digital spatial profiling of proteins and RNA in fixed tissue.
Merritt CR, Ong GT, Church SE, Barker K, Danaher P, Geiss G, Hoang M, Jung J, Liang Y, McKay-Fleisch J, Nguyen K, Norgaard Z, Sorg K, Sprague I, Warren C, Warren S, Webster PJ, Zhou Z, Zollinger DR, Dunaway DL, Mills GB, Beechem JM. Merritt CR, et al. Among authors: beechem jm. Nat Biotechnol. 2020 May;38(5):586-599. doi: 10.1038/s41587-020-0472-9. Epub 2020 May 11. Nat Biotechnol. 2020. PMID: 32393914
Spatially resolved whole transcriptome profiling in human and mouse tissue using Digital Spatial Profiling.
Zimmerman SM, Fropf R, Kulasekara BR, Griswold M, Appelbe O, Bahrami A, Boykin R, Buhr DL, Fuhrman K, Hoang ML, Huynh Q, Isgur L, Klock A, Kutchma A, Lasley AE, Liang Y, McKay-Fleisch J, Nelson JS, Nguyen K, Piazza E, Rininger A, Zollinger DR, Rhodes M, Beechem JM. Zimmerman SM, et al. Among authors: beechem jm. Genome Res. 2022 Oct;32(10):1892-1905. doi: 10.1101/gr.276206.121. Epub 2022 Sep 13. Genome Res. 2022. PMID: 36100434 Free PMC article.
High-plex imaging of RNA and proteins at subcellular resolution in fixed tissue by spatial molecular imaging.
He S, Bhatt R, Brown C, Brown EA, Buhr DL, Chantranuvatana K, Danaher P, Dunaway D, Garrison RG, Geiss G, Gregory MT, Hoang ML, Khafizov R, Killingbeck EE, Kim D, Kim TK, Kim Y, Klock A, Korukonda M, Kutchma A, Lewis ZR, Liang Y, Nelson JS, Ong GT, Perillo EP, Phan JC, Phan-Everson T, Piazza E, Rane T, Reitz Z, Rhodes M, Rosenbloom A, Ross D, Sato H, Wardhani AW, Williams-Wietzikoski CA, Wu L, Beechem JM. He S, et al. Among authors: beechem jm. Nat Biotechnol. 2022 Dec;40(12):1794-1806. doi: 10.1038/s41587-022-01483-z. Epub 2022 Oct 6. Nat Biotechnol. 2022. PMID: 36203011
Multiplatform Analysis of Intratumoral PTEN Heterogeneity in Melanoma.
Chagani S, De Macedo MP, Carapeto F, Wang F, Marzese DM, Wani K, Haydu LE, Peng W, Ong GT, Warren SE, Beechem JM, Hoon DSB, Mills GB, Tetzlaff MT, Lazar AJ, Kwong LN, Davies MA. Chagani S, et al. Among authors: beechem jm. J Invest Dermatol. 2023 Sep;143(9):1779-1787.e1. doi: 10.1016/j.jid.2023.01.034. Epub 2023 Mar 4. J Invest Dermatol. 2023. PMID: 36871660
111 results