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Ythdf is a N6-methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila.
Worpenberg L, Paolantoni C, Longhi S, Mulorz MM, Lence T, Wessels HH, Dassi E, Aiello G, Sutandy FXR, Scheibe M, Edupuganti RR, Busch A, Möckel MM, Vermeulen M, Butter F, König J, Notarangelo M, Ohler U, Dieterich C, Quattrone A, Soldano A, Roignant JY. Worpenberg L, et al. Among authors: roignant jy. EMBO J. 2021 Feb 15;40(4):e104975. doi: 10.15252/embj.2020104975. Epub 2021 Jan 11. EMBO J. 2021. PMID: 33428246 Free PMC article.
m6A modulates neuronal functions and sex determination in Drosophila.
Lence T, Akhtar J, Bayer M, Schmid K, Spindler L, Ho CH, Kreim N, Andrade-Navarro MA, Poeck B, Helm M, Roignant JY. Lence T, et al. Among authors: roignant jy. Nature. 2016 Dec 8;540(7632):242-247. doi: 10.1038/nature20568. Epub 2016 Nov 30. Nature. 2016. PMID: 27919077
The developmental proteome of Drosophila melanogaster.
Casas-Vila N, Bluhm A, Sayols S, Dinges N, Dejung M, Altenhein T, Kappei D, Altenhein B, Roignant JY, Butter F. Casas-Vila N, et al. Among authors: roignant jy. Genome Res. 2017 Jul;27(7):1273-1285. doi: 10.1101/gr.213694.116. Epub 2017 Apr 5. Genome Res. 2017. PMID: 28381612 Free PMC article.
Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d.
Knuckles P, Lence T, Haussmann IU, Jacob D, Kreim N, Carl SH, Masiello I, Hares T, Villaseñor R, Hess D, Andrade-Navarro MA, Biggiogera M, Helm M, Soller M, Bühler M, Roignant JY. Knuckles P, et al. Among authors: roignant jy. Genes Dev. 2018 Mar 1;32(5-6):415-429. doi: 10.1101/gad.309146.117. Epub 2018 Mar 13. Genes Dev. 2018. PMID: 29535189 Free PMC article.
Mechanistic insights into m6A RNA enzymes.
Lence T, Paolantoni C, Worpenberg L, Roignant JY. Lence T, et al. Among authors: roignant jy. Biochim Biophys Acta Gene Regul Mech. 2019 Mar;1862(3):222-229. doi: 10.1016/j.bbagrm.2018.10.014. Epub 2018 Nov 3. Biochim Biophys Acta Gene Regul Mech. 2019. PMID: 30395944 Review.
48 results