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An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence.
Dhimolea E, de Matos Simoes R, Kansara D, Al'Khafaji A, Bouyssou J, Weng X, Sharma S, Raja J, Awate P, Shirasaki R, Tang H, Glassner BJ, Liu Z, Gao D, Bryan J, Bender S, Roth J, Scheffer M, Jeselsohn R, Gray NS, Georgakoudi I, Vazquez F, Tsherniak A, Chen Y, Welm A, Duy C, Melnick A, Bartholdy B, Brown M, Culhane AC, Mitsiades CS. Dhimolea E, et al. Among authors: de matos simoes r. Cancer Cell. 2021 Feb 8;39(2):240-256.e11. doi: 10.1016/j.ccell.2020.12.002. Epub 2021 Jan 7. Cancer Cell. 2021. PMID: 33417832 Free PMC article.
NF-κB dysregulation in multiple myeloma.
Matthews GM, de Matos Simoes R, Dhimolea E, Sheffer M, Gandolfi S, Dashevsky O, Sorrell JD, Mitsiades CS. Matthews GM, et al. Among authors: de matos simoes r. Semin Cancer Biol. 2016 Aug;39:68-76. doi: 10.1016/j.semcancer.2016.08.005. Epub 2016 Aug 17. Semin Cancer Biol. 2016. PMID: 27544796 Review.
Pleiotropic Mechanisms Drive Endocrine Resistance in the Three-Dimensional Bone Microenvironment.
Dhimolea E, de Matos Simoes R, Kansara D, Weng X, Sharma S, Awate P, Liu Z, Gao D, Mitsiades N, Schwab JH, Chen Y, Jeselsohn R, Culhane AC, Brown M, Georgakoudi I, Mitsiades CS. Dhimolea E, et al. Among authors: de matos simoes r. Cancer Res. 2021 Jan 15;81(2):371-383. doi: 10.1158/0008-5472.CAN-20-0571. Epub 2020 Aug 28. Cancer Res. 2021. PMID: 32859606 Free PMC article.
Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins.
Shirasaki R, Matthews GM, Gandolfi S, de Matos Simoes R, Buckley DL, Raja Vora J, Sievers QL, Brüggenthies JB, Dashevsky O, Poarch H, Tang H, Bariteau MA, Sheffer M, Hu Y, Downey-Kopyscinski SL, Hengeveld PJ, Glassner BJ, Dhimolea E, Ott CJ, Zhang T, Kwiatkowski NP, Laubach JP, Schlossman RL, Richardson PG, Culhane AC, Groen RWJ, Fischer ES, Vazquez F, Tsherniak A, Hahn WC, Levy J, Auclair D, Licht JD, Keats JJ, Boise LH, Ebert BL, Bradner JE, Gray NS, Mitsiades CS. Shirasaki R, et al. Among authors: de matos simoes r. Cell Rep. 2021 Jan 5;34(1):108532. doi: 10.1016/j.celrep.2020.108532. Cell Rep. 2021. PMID: 33406420 Free PMC article.
Highly specific intracellular ubiquitination of a small molecule.
Li W, Garcia-Rivera EM, Mitchell DC, Chick JM, Maetani M, Knapp JM, Matthews GM, Shirasaki R, de Matos Simoes R, Viswanathan V, Pulice JL, Rees MG, Roth JA, Gygi SP, Mitsiades CS, Kadoch C, Schreiber SL, Ostrem JML. Li W, et al. Among authors: de matos simoes r. bioRxiv [Preprint]. 2024 Jan 28:2024.01.26.577493. doi: 10.1101/2024.01.26.577493. bioRxiv. 2024. PMID: 38328167 Free PMC article. Preprint.
TSPAN6 is a suppressor of Ras-driven cancer.
Humbert PO, Pryjda TZ, Pranjic B, Farrell A, Fujikura K, de Matos Simoes R, Karim R, Kozieradzki I, Cronin SJF, Neely GG, Meyer TF, Hagelkruys A, Richardson HE, Penninger JM. Humbert PO, et al. Among authors: de matos simoes r. Oncogene. 2022 Apr;41(14):2095-2105. doi: 10.1038/s41388-022-02223-y. Epub 2022 Feb 19. Oncogene. 2022. PMID: 35184157 Free PMC article.
Correction: TSPAN6 is a suppressor of Ras-driven cancer.
Humbert PO, Pryjda TZ, Pranjic B, Farrell A, Fujikura K, de Matos Simoes R, Karim R, Kozieradzki I, Cronin SJF, Neely GG, Meyer TF, Hagelkruys A, Richardson HE, Penninger JM. Humbert PO, et al. Among authors: de matos simoes r. Oncogene. 2022 Apr;41(14):2138. doi: 10.1038/s41388-022-02265-2. Oncogene. 2022. PMID: 35292775 Free PMC article. No abstract available.
28 results