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A STAT3 inhibitor ameliorates CNS autoimmunity by restoring Teff:Treg balance.
JCI Insight. 2021 Feb 22;6(4):e142376. doi: 10.1172/jci.insight.142376.
JCI Insight. 2021.
PMID: 33411696
Free PMC article.
Novel small molecule IL-6 inhibitor suppresses autoreactive Th17 development and promotes Treg development.
Aqel SI, Kraus EE, Jena N, Kumari V, Granitto MC, Mao L, Farinas MF, Zhao EY, Perottino G, Pei W, Lovett-Racke AE, Racke MK, Fuchs JR, Li C, Yang Y.
Aqel SI, et al.
Clin Exp Immunol. 2019 May;196(2):215-225. doi: 10.1111/cei.13258. Epub 2019 Jan 24.
Clin Exp Immunol. 2019.
PMID: 30615197
Free PMC article.
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Distinct roles for Blimp-1 in autoreactive CD4 T cells during priming and effector phase of autoimmune encephalomyelitis.
Aqel SI, Granitto MC, Nuro-Gyina PK, Pei W, Liu Y, Lovett-Racke AE, Racke MK, Yang Y.
Aqel SI, et al.
J Neuroimmunol. 2018 Dec 15;325:20-28. doi: 10.1016/j.jneuroim.2018.10.007. Epub 2018 Oct 15.
J Neuroimmunol. 2018.
PMID: 30366205
Free PMC article.
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Regulation of effector function of CNS autoreactive CD4 T cells through inhibitory receptors and IL-7Rα.
Nuro-Gyina PK, Rieser EL, Granitto MC, Pei W, Liu Y, Lee PW, Aqel S, Zhang J, Lovett-Racke AE, Racke MK, Yang Y.
Nuro-Gyina PK, et al.
J Neuroinflammation. 2016 Dec 3;13(1):302. doi: 10.1186/s12974-016-0768-3.
J Neuroinflammation. 2016.
PMID: 27912762
Free PMC article.
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Daily Moderate Exercise Is Beneficial and Social Stress Is Detrimental to Disease Pathology in Murine Lupus Nephritis.
Aqel SI, Hampton JM, Bruss M, Jones KT, Valiente GR, Wu LC, Young MC, Willis WL, Ardoin S, Agarwal S, Bolon B, Powell N, Sheridan J, Schlesinger N, Jarjour WN, Young NA.
Aqel SI, et al.
Front Physiol. 2017 Apr 26;8:236. doi: 10.3389/fphys.2017.00236. eCollection 2017.
Front Physiol. 2017.
PMID: 28491039
Free PMC article.
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