Cravatt BF - Search Results

1

Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries.

Kuljanin M, Mitchell DC, Schweppe DK, Gikandi AS, Nusinow DP, Bulloch NJ, Vinogradova EV, Wilson DL, Kool ET, Mancias JD, Cravatt BF, Gygi SP. Kuljanin M, et al. Among authors: cravatt bf. Nat Biotechnol. 2021 May;39(5):630-641. doi: 10.1038/s41587-020-00778-3. Epub 2021 Jan 4. Nat Biotechnol. 2021. PMID: 33398154 Free PMC article.

2

Proteomic profiling of mechanistically distinct enzyme classes using a common chemotype.

Adam GC, Sorensen EJ, Cravatt BF. Adam GC, et al. Among authors: cravatt bf. Nat Biotechnol. 2002 Aug;20(8):805-9. doi: 10.1038/nbt714. Epub 2002 Jul 1. Nat Biotechnol. 2002. PMID: 12091914

3

Discovering potent and selective reversible inhibitors of enzymes in complex proteomes.

Leung D, Hardouin C, Boger DL, Cravatt BF. Leung D, et al. Among authors: cravatt bf. Nat Biotechnol. 2003 Jun;21(6):687-91. doi: 10.1038/nbt826. Epub 2003 May 12. Nat Biotechnol. 2003. PMID: 12740587

4

Target discovery in small-molecule cell-based screens by in situ proteome reactivity profiling.

Evans MJ, Saghatelian A, Sorensen EJ, Cravatt BF. Evans MJ, et al. Among authors: cravatt bf. Nat Biotechnol. 2005 Oct;23(10):1303-7. doi: 10.1038/nbt1149. Epub 2005 Oct 2. Nat Biotechnol. 2005. PMID: 16200062

5

Assessing enzyme activities using stable isotope labeling and mass spectrometry.

Everley PA, Gartner CA, Haas W, Saghatelian A, Elias JE, Cravatt BF, Zetter BR, Gygi SP. Everley PA, et al. Among authors: cravatt bf. Mol Cell Proteomics. 2007 Oct;6(10):1771-7. doi: 10.1074/mcp.M700057-MCP200. Epub 2007 Jul 11. Mol Cell Proteomics. 2007. PMID: 17627935 Free article.

6

Activity-based protein profiling for the functional annotation of enzymes.

Barglow KT, Cravatt BF. Barglow KT, et al. Among authors: cravatt bf. Nat Methods. 2007 Oct;4(10):822-7. doi: 10.1038/nmeth1092. Nat Methods. 2007. PMID: 17901872 Review.

7

The biological impact of mass-spectrometry-based proteomics.

Cravatt BF, Simon GM, Yates JR 3rd. Cravatt BF, et al. Nature. 2007 Dec 13;450(7172):991-1000. doi: 10.1038/nature06525. Nature. 2007. PMID: 18075578 Review.

8

Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes.

Bachovchin DA, Brown SJ, Rosen H, Cravatt BF. Bachovchin DA, et al. Among authors: cravatt bf. Nat Biotechnol. 2009 Apr;27(4):387-94. doi: 10.1038/nbt.1531. Epub 2009 Mar 29. Nat Biotechnol. 2009. PMID: 19329999 Free PMC article.

9

Quantitative reactivity profiling predicts functional cysteines in proteomes.

Weerapana E, Wang C, Simon GM, Richter F, Khare S, Dillon MB, Bachovchin DA, Mowen K, Baker D, Cravatt BF. Weerapana E, et al. Among authors: cravatt bf. Nature. 2010 Dec 9;468(7325):790-5. doi: 10.1038/nature09472. Epub 2010 Nov 17. Nature. 2010. PMID: 21085121 Free PMC article.

10

Global profiling of dynamic protein palmitoylation.

Martin BR, Wang C, Adibekian A, Tully SE, Cravatt BF. Martin BR, et al. Among authors: cravatt bf. Nat Methods. 2011 Nov 6;9(1):84-9. doi: 10.1038/nmeth.1769. Nat Methods. 2011. PMID: 22056678 Free PMC article.

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