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p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response.
Kageyama S, Gudmundsson SR, Sou YS, Ichimura Y, Tamura N, Kazuno S, Ueno T, Miura Y, Noshiro D, Abe M, Mizushima T, Miura N, Okuda S, Motohashi H, Lee JA, Sakimura K, Ohe T, Noda NN, Waguri S, Eskelinen EL, Komatsu M. Kageyama S, et al. Among authors: okuda s. Nat Commun. 2021 Jan 4;12(1):16. doi: 10.1038/s41467-020-20185-1. Nat Commun. 2021. PMID: 33397898 Free PMC article.
p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming.
Saito T, Ichimura Y, Taguchi K, Suzuki T, Mizushima T, Takagi K, Hirose Y, Nagahashi M, Iso T, Fukutomi T, Ohishi M, Endo K, Uemura T, Nishito Y, Okuda S, Obata M, Kouno T, Imamura R, Tada Y, Obata R, Yasuda D, Takahashi K, Fujimura T, Pi J, Lee MS, Ueno T, Ohe T, Mashino T, Wakai T, Kojima H, Okabe T, Nagano T, Motohashi H, Waguri S, Soga T, Yamamoto M, Tanaka K, Komatsu M. Saito T, et al. Among authors: okuda s. Nat Commun. 2016 Jun 27;7:12030. doi: 10.1038/ncomms12030. Nat Commun. 2016. PMID: 27345495 Free PMC article.
Autophagy regulates lipid metabolism through selective turnover of NCoR1.
Saito T, Kuma A, Sugiura Y, Ichimura Y, Obata M, Kitamura H, Okuda S, Lee HC, Ikeda K, Kanegae Y, Saito I, Auwerx J, Motohashi H, Suematsu M, Soga T, Yokomizo T, Waguri S, Mizushima N, Komatsu M. Saito T, et al. Among authors: okuda s. Nat Commun. 2019 Apr 5;10(1):1567. doi: 10.1038/s41467-019-08829-3. Nat Commun. 2019. PMID: 30952864 Free PMC article.
Activin a Receptor Type 2A Mutation Affects the Tumor Biology of Microsatellite Instability-High Gastric Cancer.
Yuza K, Nagahashi M, Ichikawa H, Hanyu T, Nakajima M, Shimada Y, Ishikawa T, Sakata J, Takeuchi S, Okuda S, Matsuda Y, Abe M, Sakimura K, Takabe K, Wakai T. Yuza K, et al. Among authors: okuda s. J Gastrointest Surg. 2021 Sep;25(9):2231-2241. doi: 10.1007/s11605-020-04889-9. Epub 2021 Jan 8. J Gastrointest Surg. 2021. PMID: 33420656 Free PMC article.
Loss of Atg2b and Gskip Impairs the Maintenance of the Hematopoietic Stem Cell Pool Size.
Sakai SS, Hasegawa A, Ishimura R, Tamura N, Kageyama S, Komatsu-Hirota S, Abe M, Ling Y, Okuda S, Funayama M, Kikkawa M, Miura Y, Sakimura K, Narita I, Waguri S, Shimizu R, Komatsu M. Sakai SS, et al. Among authors: okuda s. Mol Cell Biol. 2022 Jan 20;42(1):e0002421. doi: 10.1128/MCB.00024-21. Epub 2021 Nov 8. Mol Cell Biol. 2022. PMID: 34748402 Free PMC article.
Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity.
Hayashi Y, Shimizu I, Yoshida Y, Ikegami R, Suda M, Katsuumi G, Fujiki S, Ozaki K, Abe M, Sakimura K, Okuda S, Hayano T, Nakamura K, Walsh K, Jespersen NZ, Nielsen S, Scheele C, Minamino T. Hayashi Y, et al. Among authors: okuda s. iScience. 2022 Jun 7;25(7):104547. doi: 10.1016/j.isci.2022.104547. eCollection 2022 Jul 15. iScience. 2022. PMID: 35754738 Free PMC article.
Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism.
Yoshida Y, Shimizu I, Shimada A, Nakahara K, Yanagisawa S, Kubo M, Fukuda S, Ishii C, Yamamoto H, Ishikawa T, Kano K, Aoki J, Katsuumi G, Suda M, Ozaki K, Yoshida Y, Okuda S, Ohta S, Okamoto S, Minokoshi Y, Oda K, Sasaoka T, Abe M, Sakimura K, Kubota Y, Yoshimura N, Kajimura S, Zuriaga M, Walsh K, Soga T, Minamino T. Yoshida Y, et al. Among authors: okuda s. Sci Rep. 2022 Sep 1;12(1):14883. doi: 10.1038/s41598-022-19245-x. Sci Rep. 2022. PMID: 36050466 Free PMC article.
Towards a standardized bioinformatics infrastructure for N- and O-glycomics.
Rojas-Macias MA, Mariethoz J, Andersson P, Jin C, Venkatakrishnan V, Aoki NP, Shinmachi D, Ashwood C, Madunic K, Zhang T, Miller RL, Horlacher O, Struwe WB, Watanabe Y, Okuda S, Levander F, Kolarich D, Rudd PM, Wuhrer M, Kettner C, Packer NH, Aoki-Kinoshita KF, Lisacek F, Karlsson NG. Rojas-Macias MA, et al. Among authors: okuda s. Nat Commun. 2019 Jul 22;10(1):3275. doi: 10.1038/s41467-019-11131-x. Nat Commun. 2019. PMID: 31332201 Free PMC article. Review.
1,280 results