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Human skin is colonized by T cells that recognize CD1a independently of lipid.
Cotton RN, Cheng TY, Wegrecki M, Le Nours J, Orgill DP, Pomahac B, Talbot SG, Willis RA, Altman JD, de Jong A, Ogg G, Van Rhijn I, Rossjohn J, Clark RA, Moody DB. Cotton RN, et al. Among authors: le nours j. J Clin Invest. 2021 Jan 4;131(1):e140706. doi: 10.1172/JCI140706. J Clin Invest. 2021. PMID: 33393500 Free PMC article.
Structure, biological functions and applications of the AB5 toxins.
Beddoe T, Paton AW, Le Nours J, Rossjohn J, Paton JC. Beddoe T, et al. Among authors: le nours j. Trends Biochem Sci. 2010 Jul;35(7):411-8. doi: 10.1016/j.tibs.2010.02.003. Epub 2010 Mar 2. Trends Biochem Sci. 2010. PMID: 20202851 Free PMC article. Review.
MR1 presents microbial vitamin B metabolites to MAIT cells.
Kjer-Nielsen L, Patel O, Corbett AJ, Le Nours J, Meehan B, Liu L, Bhati M, Chen Z, Kostenko L, Reantragoon R, Williamson NA, Purcell AW, Dudek NL, McConville MJ, O'Hair RA, Khairallah GN, Godfrey DI, Fairlie DP, Rossjohn J, McCluskey J. Kjer-Nielsen L, et al. Among authors: le nours j. Nature. 2012 Nov 29;491(7426):717-23. doi: 10.1038/nature11605. Epub 2012 Oct 10. Nature. 2012. PMID: 23051753
Recognition of vitamin B metabolites by mucosal-associated invariant T cells.
Patel O, Kjer-Nielsen L, Le Nours J, Eckle SB, Birkinshaw R, Beddoe T, Corbett AJ, Liu L, Miles JJ, Meehan B, Reantragoon R, Sandoval-Romero ML, Sullivan LC, Brooks AG, Chen Z, Fairlie DP, McCluskey J, Rossjohn J. Patel O, et al. Among authors: le nours j. Nat Commun. 2013;4:2142. doi: 10.1038/ncomms3142. Nat Commun. 2013. PMID: 23846752 Free article.
Structural basis of subtilase cytotoxin SubAB assembly.
Le Nours J, Paton AW, Byres E, Troy S, Herdman BP, Johnson MD, Paton JC, Rossjohn J, Beddoe T. Le Nours J, et al. J Biol Chem. 2013 Sep 20;288(38):27505-27516. doi: 10.1074/jbc.M113.462622. Epub 2013 Aug 6. J Biol Chem. 2013. PMID: 23921389 Free PMC article.
CD1d-lipid antigen recognition by the γδ TCR.
Uldrich AP, Le Nours J, Pellicci DG, Gherardin NA, McPherson KG, Lim RT, Patel O, Beddoe T, Gras S, Rossjohn J, Godfrey DI. Uldrich AP, et al. Among authors: le nours j. Nat Immunol. 2013 Nov;14(11):1137-45. doi: 10.1038/ni.2713. Epub 2013 Sep 29. Nat Immunol. 2013. PMID: 24076636
53 results