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Assessment of the biochemical pathways for acetaminophen toxicity: Implications for its carcinogenic hazard potential.
Jaeschke H, Murray FJ, Monnot AD, Jacobson-Kram D, Cohen SM, Hardisty JF, Atillasoy E, Hermanowski-Vosatka A, Kuffner E, Wikoff D, Chappell GA, Bandara SB, Deore M, Pitchaiyan SK, Eichenbaum G. Jaeschke H, et al. Among authors: murray fj. Regul Toxicol Pharmacol. 2021 Mar;120:104859. doi: 10.1016/j.yrtph.2020.104859. Epub 2021 Jan 1. Regul Toxicol Pharmacol. 2021. PMID: 33388367 Free article. Review.
A critical review of the acetaminophen preclinical carcinogenicity and tumor promotion data and their implications for its carcinogenic hazard potential.
Murray FJ, Monnot AD, Jacobson-Kram D, Cohen SM, Hardisty JF, Bandara SB, Kovochich M, Deore M, Pitchaiyan SK, Gelotte CK, Lai JCK, Atillasoy E, Hermanowski-Vosatka A, Kuffner E, Unice KM, Yang K, Gebremichael Y, Howell BA, Eichenbaum G. Murray FJ, et al. Regul Toxicol Pharmacol. 2020 Dec;118:104801. doi: 10.1016/j.yrtph.2020.104801. Epub 2020 Oct 9. Regul Toxicol Pharmacol. 2020. PMID: 33039518 Free article. Review.
Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen.
Eichenbaum G, Yang K, Gebremichael Y, Howell BA, Murray FJ, Jacobson-Kram D, Jaeschke H, Kuffner E, Gelotte CK, Lai JCK, Wikoff D, Atillasoy E. Eichenbaum G, et al. Among authors: murray fj. Regul Toxicol Pharmacol. 2020 Dec;118:104788. doi: 10.1016/j.yrtph.2020.104788. Epub 2020 Oct 22. Regul Toxicol Pharmacol. 2020. PMID: 33153971 Free article.
A comprehensive weight of evidence assessment of published acetaminophen genotoxicity data: Implications for its carcinogenic hazard potential.
Kirkland D, Kovochich M, More SL, Murray FJ, Monnot AD, Miller JV, Jaeschke H, Jacobson-Kram D, Deore M, Pitchaiyan SK, Unice K, Eichenbaum G. Kirkland D, et al. Among authors: murray fj. Regul Toxicol Pharmacol. 2021 Jun;122:104892. doi: 10.1016/j.yrtph.2021.104892. Epub 2021 Feb 13. Regul Toxicol Pharmacol. 2021. PMID: 33592196 Free article. Review.
95 results