Nakata T - Search Results

1

QRICH1 dictates the outcome of ER stress through transcriptional control of proteostasis.

You K, Wang L, Chou CH, Liu K, Nakata T, Jaiswal A, Yao J, Lefkovith A, Omar A, Perrigoue JG, Towne JE, Regev A, Graham DB, Xavier RJ. You K, et al. Among authors: nakata t. Science. 2021 Jan 1;371(6524):eabb6896. doi: 10.1126/science.abb6896. Science. 2021. PMID: 33384352 Free PMC article.

2

C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions.

Mohanan V, Nakata T, Desch AN, Lévesque C, Boroughs A, Guzman G, Cao Z, Creasey E, Yao J, Boucher G, Charron G, Bhan AK, Schenone M, Carr SA, Reinecker HC, Daly MJ, Rioux JD, Lassen KG, Xavier RJ. Mohanan V, et al. Among authors: nakata t. Science. 2018 Mar 9;359(6380):1161-1166. doi: 10.1126/science.aan0814. Epub 2018 Feb 1. Science. 2018. PMID: 29420262 Free PMC article.

3

Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis.

Brown EM, Ke X, Hitchcock D, Jeanfavre S, Avila-Pacheco J, Nakata T, Arthur TD, Fornelos N, Heim C, Franzosa EA, Watson N, Huttenhower C, Haiser HJ, Dillow G, Graham DB, Finlay BB, Kostic AD, Porter JA, Vlamakis H, Clish CB, Xavier RJ. Brown EM, et al. Among authors: nakata t. Cell Host Microbe. 2019 May 8;25(5):668-680.e7. doi: 10.1016/j.chom.2019.04.002. Cell Host Microbe. 2019. PMID: 31071294 Free PMC article.

4

A missense variant in SLC39A8 confers risk for Crohn's disease by disrupting manganese homeostasis and intestinal barrier integrity.

Nakata T, Creasey EA, Kadoki M, Lin H, Selig MK, Yao J, Lefkovith A, Daly MJ, Graham DB, Xavier RJ. Nakata T, et al. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):28930-28938. doi: 10.1073/pnas.2014742117. Epub 2020 Nov 2. Proc Natl Acad Sci U S A. 2020. PMID: 33139556 Free PMC article.

5

The schizophrenia-associated variant in SLC39A8 alters protein glycosylation in the mouse brain.

Mealer RG, Williams SE, Noel M, Yang B, D'Souza AK, Nakata T, Graham DB, Creasey EA, Cetinbas M, Sadreyev RI, Scolnick EM, Woo CM, Smoller JW, Xavier RJ, Cummings RD. Mealer RG, et al. Among authors: nakata t. Mol Psychiatry. 2022 Mar;27(3):1405-1415. doi: 10.1038/s41380-022-01490-1. Epub 2022 Mar 8. Mol Psychiatry. 2022. PMID: 35260802 Free PMC article.

6

Genetic vulnerability to Crohn's disease reveals a spatially resolved epithelial restitution program.

Nakata T, Li C, Mayassi T, Lin H, Ghosh K, Segerstolpe Å, Diamond EL, Herbst P, Biancalani T, Gaddam S, Parkar S, Lu Z, Jaiswal A, Li B, Creasey EA, Lefkovith A, Daly MJ, Graham DB, Xavier RJ. Nakata T, et al. Sci Transl Med. 2023 Oct 25;15(719):eadg5252. doi: 10.1126/scitranslmed.adg5252. Epub 2023 Oct 25. Sci Transl Med. 2023. PMID: 37878672 Free PMC article.

7

PGE₂ is a direct and robust mediator of anion/fluid secretion by human intestinal epithelial cells.

Fujii S, Suzuki K, Kawamoto A, Ishibashi F, Nakata T, Murano T, Ito G, Shimizu H, Mizutani T, Oshima S, Tsuchiya K, Nakamura T, Araki A, Ohtsuka K, Okamoto R, Watanabe M. Fujii S, et al. Among authors: nakata t. Sci Rep. 2016 Nov 9;6:36795. doi: 10.1038/srep36795. Sci Rep. 2016. PMID: 27827428 Free PMC article.

8

Lineage-specific expression of bestrophin-2 and bestrophin-4 in human intestinal epithelial cells.

Ito G, Okamoto R, Murano T, Shimizu H, Fujii S, Nakata T, Mizutani T, Yui S, Akiyama-Morio J, Nemoto Y, Okada E, Araki A, Ohtsuka K, Tsuchiya K, Nakamura T, Watanabe M. Ito G, et al. Among authors: nakata t. PLoS One. 2013 Nov 5;8(11):e79693. doi: 10.1371/journal.pone.0079693. eCollection 2013. PLoS One. 2013. PMID: 24223998 Free PMC article.

9

Hes1 promotes the IL-22-mediated antimicrobial response by enhancing STAT3-dependent transcription in human intestinal epithelial cells.

Murano T, Okamoto R, Ito G, Nakata T, Hibiya S, Shimizu H, Fujii S, Kano Y, Mizutani T, Yui S, Akiyama-Morio J, Nemoto Y, Tsuchiya K, Nakamura T, Watanabe M. Murano T, et al. Among authors: nakata t. Biochem Biophys Res Commun. 2014 Jan 17;443(3):840-6. doi: 10.1016/j.bbrc.2013.12.061. Epub 2013 Dec 14. Biochem Biophys Res Commun. 2014. PMID: 24342613

10

Distinct expression patterns of Notch ligands, Dll1 and Dll4, in normal and inflamed mice intestine.

Shimizu H, Okamoto R, Ito G, Fujii S, Nakata T, Suzuki K, Murano T, Mizutani T, Tsuchiya K, Nakamura T, Hozumi K, Watanabe M. Shimizu H, et al. Among authors: nakata t. PeerJ. 2014 May 1;2:e370. doi: 10.7717/peerj.370. eCollection 2014. PeerJ. 2014. PMID: 24860699 Free PMC article.

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