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In situ genome sequencing resolves DNA sequence and structure in intact biological samples.
Payne AC, Chiang ZD, Reginato PL, Mangiameli SM, Murray EM, Yao CC, Markoulaki S, Earl AS, Labade AS, Jaenisch R, Church GM, Boyden ES, Buenrostro JD, Chen F. Payne AC, et al. Among authors: murray em. Science. 2021 Feb 26;371(6532):eaay3446. doi: 10.1126/science.aay3446. Epub 2020 Dec 31. Science. 2021. PMID: 33384301 Free PMC article.
Compressed sensing for highly efficient imaging transcriptomics.
Cleary B, Simonton B, Bezney J, Murray E, Alam S, Sinha A, Habibi E, Marshall J, Lander ES, Chen F, Regev A. Cleary B, et al. Nat Biotechnol. 2021 Aug;39(8):936-942. doi: 10.1038/s41587-021-00883-x. Epub 2021 Apr 15. Nat Biotechnol. 2021. PMID: 33859401 Free PMC article.
Dissecting mammalian spermatogenesis using spatial transcriptomics.
Chen H, Murray E, Sinha A, Laumas A, Li J, Lesman D, Nie X, Hotaling J, Guo J, Cairns BR, Macosko EZ, Cheng CY, Chen F. Chen H, et al. Cell Rep. 2021 Nov 2;37(5):109915. doi: 10.1016/j.celrep.2021.109915. Cell Rep. 2021. PMID: 34731600 Free PMC article.
Spatial genomics enables multi-modal study of clonal heterogeneity in tissues.
Zhao T, Chiang ZD, Morriss JW, LaFave LM, Murray EM, Del Priore I, Meli K, Lareau CA, Nadaf NM, Li J, Earl AS, Macosko EZ, Jacks T, Buenrostro JD, Chen F. Zhao T, et al. Among authors: murray em. Nature. 2022 Jan;601(7891):85-91. doi: 10.1038/s41586-021-04217-4. Epub 2021 Dec 15. Nature. 2022. PMID: 34912115 Free PMC article.
High-resolution Slide-seqV2 spatial transcriptomics enables discovery of disease-specific cell neighborhoods and pathways.
Marshall JL, Noel T, Wang QS, Chen H, Murray E, Subramanian A, Vernon KA, Bazua-Valenti S, Liguori K, Keller K, Stickels RR, McBean B, Heneghan RM, Weins A, Macosko EZ, Chen F, Greka A. Marshall JL, et al. iScience. 2022 Mar 16;25(4):104097. doi: 10.1016/j.isci.2022.104097. eCollection 2022 Apr 15. iScience. 2022. PMID: 35372810 Free PMC article.
Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex.
Uzquiano A, Kedaigle AJ, Pigoni M, Paulsen B, Adiconis X, Kim K, Faits T, Nagaraja S, Antón-Bolaños N, Gerhardinger C, Tucewicz A, Murray E, Jin X, Buenrostro J, Chen F, Velasco S, Regev A, Levin JZ, Arlotta P. Uzquiano A, et al. Cell. 2022 Sep 29;185(20):3770-3788.e27. doi: 10.1016/j.cell.2022.09.010. Cell. 2022. PMID: 36179669 Free PMC article.
60 results