Heikura T - Search Results

1

Efficacy and Safety of Clinical-Grade Human Vascular Endothelial Growth Factor-D^ΔNΔC Gene Therapy Containing Residual Replication-Competent Adenoviruses.

Leikas AJ, Laham-Karam N, Agtereek E, Peltonen HM, Selander T, Korpisalo P, Holappa L, Hartikainen JEK, Heikura T, Ylä-Herttuala S. Leikas AJ, et al. Among authors: heikura t. Hum Gene Ther. 2021 Jul;32(13-14):761-770. doi: 10.1089/hum.2020.299. Epub 2021 Mar 4. Hum Gene Ther. 2021. PMID: 33371775

2

Extracellular superoxide dismutase with vaccinia virus anti-inflammatory protein 35K or tissue inhibitor of metalloproteinase-1: Combination gene therapy in the treatment of vein graft stenosis in rabbits.

Turunen P, Puhakka HL, Heikura T, Romppanen E, Inkala M, Leppänen O, Ylä-Herttuala S. Turunen P, et al. Among authors: heikura t. Hum Gene Ther. 2006 Apr;17(4):405-14. doi: 10.1089/hum.2006.17.405. Hum Gene Ther. 2006. PMID: 16610928

3

Intravitreal adenoviral 15-lipoxygenase-1 gene transfer prevents vascular endothelial growth factor A-induced neovascularization in rabbit eyes.

Viita H, Kinnunen K, Eriksson E, Lähteenvuo J, Babu M, Kalesnykas G, Heikura T, Laidinen S, Takalo T, Ylä-Herttuala S. Viita H, et al. Among authors: heikura t. Hum Gene Ther. 2009 Dec;20(12):1679-86. doi: 10.1089/hum.2009.069. Hum Gene Ther. 2009. PMID: 19694557

4

Baculovirus-mediated vascular endothelial growth factor-D(ΔNΔC) gene transfer induces angiogenesis in rabbit skeletal muscle.

Heikura T, Nieminen T, Roschier MM, Karvinen H, Kaikkonen MU, Mähönen AJ, Lesch HP, Rissanen TT, Laitinen OH, Airenne KJ, Ylä-Herttuala S. Heikura T, et al. J Gene Med. 2012 Jan;14(1):35-43. doi: 10.1002/jgm.1637. J Gene Med. 2012. PMID: 22162149

5

Preclinical safety, toxicology, and biodistribution study of adenoviral gene therapy with sVEGFR-2 and sVEGFR-3 combined with chemotherapy for ovarian cancer.

Tuppurainen L, Sallinen H, Kokki E, Koponen J, Anttila M, Pulkkinen K, Heikura T, Toivanen P, Hämäläinen K, Kosma VM, Heinonen S, Alitalo K, Ylä-Herttuala S. Tuppurainen L, et al. Among authors: heikura t. Hum Gene Ther Clin Dev. 2013 Mar;24(1):29-37. doi: 10.1089/humc.2013.006. Epub 2013 Apr 3. Hum Gene Ther Clin Dev. 2013. PMID: 23692381

6

Benchmarking of Scale-X Bioreactor System in Lentiviral and Adenoviral Vector Production.

Leinonen HM, Lepola S, Lipponen EM, Heikura T, Koponen T, Parker N, Ylä-Herttuala S, Lesch HP. Leinonen HM, et al. Among authors: heikura t. Hum Gene Ther. 2020 Mar;31(5-6):376-384. doi: 10.1089/hum.2019.247. Hum Gene Ther. 2020. PMID: 32075423 Free PMC article.

7

Comparison of Efficiency and Function of Vascular Endothelial Growth Factor Adenovirus Vectors in Endothelial Cells for Gene Therapy of Placental Insufficiency.

Rossi C, Lees M, Mehta V, Heikura T, Martin J, Zachary I, Spencer R, Peebles DM, Shaw R, Karhinen M, Yla-Herttuala S, David AL. Rossi C, et al. Among authors: heikura t. Hum Gene Ther. 2020 Nov;31(21-22):1190-1202. doi: 10.1089/hum.2020.006. Hum Gene Ther. 2020. PMID: 32988220 Free PMC article.

8

Baculovirus is an efficient vector for the transduction of the eye: comparison of baculovirus- and adenovirus-mediated intravitreal vascular endothelial growth factor D gene transfer in the rabbit eye.

Kinnunen K, Kalesnykas G, Mähönen AJ, Laidinen S, Holma L, Heikura T, Airenne K, Uusitalo H, Ylä-Herttuala S. Kinnunen K, et al. Among authors: heikura t. J Gene Med. 2009 May;11(5):382-9. doi: 10.1002/jgm.1311. J Gene Med. 2009. PMID: 19263462

9

Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart.

Rutanen J, Rissanen TT, Markkanen JE, Gruchala M, Silvennoinen P, Kivelä A, Hedman A, Hedman M, Heikura T, Ordén MR, Stacker SA, Achen MG, Hartikainen J, Ylä-Herttuala S. Rutanen J, et al. Among authors: heikura t. Circulation. 2004 Mar 2;109(8):1029-35. doi: 10.1161/01.CIR.0000115519.03688.A2. Epub 2004 Feb 16. Circulation. 2004. PMID: 14967735

10

Blood flow remodels growing vasculature during vascular endothelial growth factor gene therapy and determines between capillary arterialization and sprouting angiogenesis.

Rissanen TT, Korpisalo P, Markkanen JE, Liimatainen T, Ordén MR, Kholová I, de Goede A, Heikura T, Gröhn OH, Ylä-Herttuala S. Rissanen TT, et al. Among authors: heikura t. Circulation. 2005 Dec 20;112(25):3937-46. doi: 10.1161/CIRCULATIONAHA.105.543124. Epub 2005 Dec 12. Circulation. 2005. PMID: 16344386

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