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Efficacy and Safety of Clinical-Grade Human Vascular Endothelial Growth Factor-DΔNΔC Gene Therapy Containing Residual Replication-Competent Adenoviruses.
Leikas AJ, Laham-Karam N, Agtereek E, Peltonen HM, Selander T, Korpisalo P, Holappa L, Hartikainen JEK, Heikura T, Ylä-Herttuala S. Leikas AJ, et al. Among authors: hartikainen jek. Hum Gene Ther. 2021 Jul;32(13-14):761-770. doi: 10.1089/hum.2020.299. Epub 2021 Mar 4. Hum Gene Ther. 2021. PMID: 33371775
Safety and feasibility of catheter-based local intracoronary vascular endothelial growth factor gene transfer in the prevention of postangioplasty and in-stent restenosis and in the treatment of chronic myocardial ischemia: phase II results of the Kuopio Angiogenesis Trial (KAT).
Hedman M, Hartikainen J, Syvänne M, Stjernvall J, Hedman A, Kivelä A, Vanninen E, Mussalo H, Kauppila E, Simula S, Närvänen O, Rantala A, Peuhkurinen K, Nieminen MS, Laakso M, Ylä-Herttuala S. Hedman M, et al. Circulation. 2003 Jun 3;107(21):2677-83. doi: 10.1161/01.CIR.0000070540.80780.92. Epub 2003 May 12. Circulation. 2003. PMID: 12742981 Clinical Trial.
Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart.
Rutanen J, Rissanen TT, Markkanen JE, Gruchala M, Silvennoinen P, Kivelä A, Hedman A, Hedman M, Heikura T, Ordén MR, Stacker SA, Achen MG, Hartikainen J, Ylä-Herttuala S. Rutanen J, et al. Circulation. 2004 Mar 2;109(8):1029-35. doi: 10.1161/01.CIR.0000115519.03688.A2. Epub 2004 Feb 16. Circulation. 2004. PMID: 14967735
307 results