Previtali V - Search Results

1

Exploring the Anti-Cancer Mechanism of Novel 3,4'-Substituted Diaryl Guanidinium Derivatives.

Previtali V, Mihigo HB, Amet R, McElligott AM, Zisterer DM, Rozas I. Previtali V, et al. Pharmaceuticals (Basel). 2020 Dec 21;13(12):485. doi: 10.3390/ph13120485. Pharmaceuticals (Basel). 2020. PMID: 33371382 Free PMC article.

2

Effect of isouronium/guanidinium substitution on the efficacy of a series of novel anti-cancer agents.

Previtali V, Trujillo C, Amet R, Zisterer DM, Rozas I. Previtali V, et al. Medchemcomm. 2018 Mar 27;9(4):735-743. doi: 10.1039/c8md00089a. eCollection 2018 Apr 1. Medchemcomm. 2018. PMID: 30108964 Free PMC article.

3

Structure-activity relationships of new Organotin(IV) anticancer agents and their cytotoxicity profile on HL-60, MCF-7 and HeLa human cancer cell lines.

Ullah H, Previtali V, Mihigo HB, Twamley B, Rauf MK, Javed F, Waseem A, Baker RJ, Rozas I. Ullah H, et al. Among authors: previtali v. Eur J Med Chem. 2019 Nov 1;181:111544. doi: 10.1016/j.ejmech.2019.07.047. Epub 2019 Jul 16. Eur J Med Chem. 2019. PMID: 31374420

4

A novel aryl-guanidinium derivative, VP79s, targets the signal transducer and activator of transcription 3 signaling pathway, downregulates myeloid cell leukaemia-1 and exhibits preclinical activity against multiple myeloma.

Amet R, Previtali V, Mihigo HB, Sheridan E, Brophy S, Hante NK, Santos-Martinez MJ, Hayden PJ, Browne PV, Rozas I, McElligott AM, Zisterer DM. Amet R, et al. Among authors: previtali v. Life Sci. 2022 Feb 1;290:120236. doi: 10.1016/j.lfs.2021.120236. Epub 2021 Dec 22. Life Sci. 2022. PMID: 34953891

5

Development of the first model of a phosphorylated, ATP/Mg²⁺-containing B-Raf monomer by molecular dynamics simulations: a tool for structure-based design.

Previtali V, Trujillo C, Boisson JC, Khartabil H, Hénon E, Rozas I. Previtali V, et al. Phys Chem Chem Phys. 2017 Nov 29;19(46):31177-31185. doi: 10.1039/c7cp05038k. Phys Chem Chem Phys. 2017. PMID: 29139502

6

Theoretical Investigation of Cyano-Chalcogen Dimers and Their Importance in Molecular Recognition.

Previtali V, Sánchez-Sanz G, Trujillo C. Previtali V, et al. Chemphyschem. 2019 Dec 3;20(23):3186-3194. doi: 10.1002/cphc.201900899. Epub 2019 Nov 12. Chemphyschem. 2019. PMID: 31608563

7

Auxiliary in vitro and in vivo biological evaluation of hydrogen peroxide sensitive prodrugs of methotrexate and aminopterin for the treatment of rheumatoid arthritis.

Previtali V, Petrovic K, Peiró Cadahía J, Troelsen NS, Clausen MH. Previtali V, et al. Bioorg Med Chem. 2020 Jan 15;28(2):115247. doi: 10.1016/j.bmc.2019.115247. Epub 2019 Dec 6. Bioorg Med Chem. 2020. PMID: 31843461

8

Prodrug strategies for targeted therapy triggered by reactive oxygen species.

Peiró Cadahía J, Previtali V, Troelsen NS, Clausen MH. Peiró Cadahía J, et al. Among authors: previtali v. Medchemcomm. 2019 May 8;10(9):1531-1549. doi: 10.1039/c9md00169g. eCollection 2019 Sep 1. Medchemcomm. 2019. PMID: 31673314 Free PMC article. Review.

9

Synthesis and Evaluation of Hydrogen Peroxide Sensitive Prodrugs of Methotrexate and Aminopterin for the Treatment of Rheumatoid Arthritis.

Peiró Cadahía J, Bondebjerg J, Hansen CA, Previtali V, Hansen AE, Andresen TL, Clausen MH. Peiró Cadahía J, et al. Among authors: previtali v. J Med Chem. 2018 Apr 26;61(8):3503-3515. doi: 10.1021/acs.jmedchem.7b01775. Epub 2018 Apr 10. J Med Chem. 2018. PMID: 29605999

10

Methotrexate prodrugs sensitive to reactive oxygen species for the improved treatment of rheumatoid arthritis.

Andersen NS, Peiró Cadahía J, Previtali V, Bondebjerg J, Hansen CA, Hansen AE, Andresen TL, Clausen MH. Andersen NS, et al. Among authors: previtali v. Eur J Med Chem. 2018 Aug 5;156:738-746. doi: 10.1016/j.ejmech.2018.07.045. Epub 2018 Jul 20. Eur J Med Chem. 2018. PMID: 30048923

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