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Loss of phosphatase and tensin homolog (PTEN) in myeloid cells controls inflammatory bone destruction by regulating the osteoclastogenic potential of myeloid cells.
Blüml S, Friedrich M, Lohmeyer T, Sahin E, Saferding V, Brunner J, Puchner A, Mandl P, Niederreiter B, Smolen JS, Schabbauer G, Redlich K. Blüml S, et al. Among authors: schabbauer g. Ann Rheum Dis. 2015 Jan;74(1):227-33. doi: 10.1136/annrheumdis-2013-203486. Epub 2013 Sep 27. Ann Rheum Dis. 2015. PMID: 24078675
Myeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition.
Kuttke M, Sahin E, Pisoni J, Percig S, Vogel A, Kraemmer D, Hanzl L, Brunner JS, Paar H, Soukup K, Halfmann A, Dohnal AM, Steiner CW, Blüml S, Basilio J, Hochreiter B, Salzmann M, Hoesel B, Lametschwandtner G, Eferl R, Schmid JA, Schabbauer G. Kuttke M, et al. Among authors: schabbauer g. Oncoimmunology. 2016 Mar 28;5(7):e1164918. doi: 10.1080/2162402X.2016.1164918. eCollection 2016 Jul. Oncoimmunology. 2016. PMID: 27622019 Free PMC article.
MicroRNA-146a governs fibroblast activation and joint pathology in arthritis.
Saferding V, Puchner A, Goncalves-Alves E, Hofmann M, Bonelli M, Brunner JS, Sahin E, Niederreiter B, Hayer S, Kiener HP, Einwallner E, Nehmar R, Carapito R, Georgel P, Koenders MI, Boldin M, Schabbauer G, Kurowska-Stolarska M, Steiner G, Smolen JS, Redlich K, Blüml S. Saferding V, et al. Among authors: schabbauer g. J Autoimmun. 2017 Aug;82:74-84. doi: 10.1016/j.jaut.2017.05.006. Epub 2017 May 22. J Autoimmun. 2017. PMID: 28545737 Free PMC article.
PI3K activity in dendritic cells exerts paradoxical effects during autoimmune inflammation.
Datler H, Vogel A, Kerndl M, Baumgartinger C, Musiejovsky L, Makivic N, Frech S, Niederreiter B, Haider T, Pühringer M, Brunner JS, Sharif O, Schabbauer G. Datler H, et al. Among authors: schabbauer g. Mol Immunol. 2019 Jul;111:32-42. doi: 10.1016/j.molimm.2019.03.015. Epub 2019 Apr 5. Mol Immunol. 2019. PMID: 30959419 Free article.
Macrophage Rewiring by Nutrient Associated PI3K Dependent Pathways.
Sharif O, Brunner JS, Vogel A, Schabbauer G. Sharif O, et al. Among authors: schabbauer g. Front Immunol. 2019 Aug 21;10:2002. doi: 10.3389/fimmu.2019.02002. eCollection 2019. Front Immunol. 2019. PMID: 31497027 Free PMC article. Review.
Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function.
Lercher A, Bhattacharya A, Popa AM, Caldera M, Schlapansky MF, Baazim H, Agerer B, Gürtl B, Kosack L, Májek P, Brunner JS, Vitko D, Pinter T, Genger JW, Orlova A, Pikor N, Reil D, Ozsvár-Kozma M, Kalinke U, Ludewig B, Moriggl R, Bennett KL, Menche J, Cheng PN, Schabbauer G, Trauner M, Klavins K, Bergthaler A. Lercher A, et al. Among authors: schabbauer g. Immunity. 2019 Dec 17;51(6):1074-1087.e9. doi: 10.1016/j.immuni.2019.10.014. Epub 2019 Nov 26. Immunity. 2019. PMID: 31784108 Free PMC article.
Environmental arginine controls multinuclear giant cell metabolism and formation.
Brunner JS, Vulliard L, Hofmann M, Kieler M, Lercher A, Vogel A, Russier M, Brüggenthies JB, Kerndl M, Saferding V, Niederreiter B, Junza A, Frauenstein A, Scholtysek C, Mikami Y, Klavins K, Krönke G, Bergthaler A, O'Shea JJ, Weichhart T, Meissner F, Smolen JS, Cheng P, Yanes O, Menche J, Murray PJ, Sharif O, Blüml S, Schabbauer G. Brunner JS, et al. Among authors: schabbauer g. Nat Commun. 2020 Jan 22;11(1):431. doi: 10.1038/s41467-020-14285-1. Nat Commun. 2020. PMID: 31969567 Free PMC article.
81 results