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Loss of phosphatase and tensin homolog (PTEN) in myeloid cells controls inflammatory bone destruction by regulating the osteoclastogenic potential of myeloid cells.
Blüml S, Friedrich M, Lohmeyer T, Sahin E, Saferding V, Brunner J, Puchner A, Mandl P, Niederreiter B, Smolen JS, Schabbauer G, Redlich K. Blüml S, et al. Among authors: brunner j. Ann Rheum Dis. 2015 Jan;74(1):227-33. doi: 10.1136/annrheumdis-2013-203486. Epub 2013 Sep 27. Ann Rheum Dis. 2015. PMID: 24078675
PI3K activity in dendritic cells exerts paradoxical effects during autoimmune inflammation.
Datler H, Vogel A, Kerndl M, Baumgartinger C, Musiejovsky L, Makivic N, Frech S, Niederreiter B, Haider T, Pühringer M, Brunner JS, Sharif O, Schabbauer G. Datler H, et al. Among authors: brunner js. Mol Immunol. 2019 Jul;111:32-42. doi: 10.1016/j.molimm.2019.03.015. Epub 2019 Apr 5. Mol Immunol. 2019. PMID: 30959419 Free article.
Macrophage Rewiring by Nutrient Associated PI3K Dependent Pathways.
Sharif O, Brunner JS, Vogel A, Schabbauer G. Sharif O, et al. Among authors: brunner js. Front Immunol. 2019 Aug 21;10:2002. doi: 10.3389/fimmu.2019.02002. eCollection 2019. Front Immunol. 2019. PMID: 31497027 Free PMC article. Review.
Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function.
Lercher A, Bhattacharya A, Popa AM, Caldera M, Schlapansky MF, Baazim H, Agerer B, Gürtl B, Kosack L, Májek P, Brunner JS, Vitko D, Pinter T, Genger JW, Orlova A, Pikor N, Reil D, Ozsvár-Kozma M, Kalinke U, Ludewig B, Moriggl R, Bennett KL, Menche J, Cheng PN, Schabbauer G, Trauner M, Klavins K, Bergthaler A. Lercher A, et al. Among authors: brunner js. Immunity. 2019 Dec 17;51(6):1074-1087.e9. doi: 10.1016/j.immuni.2019.10.014. Epub 2019 Nov 26. Immunity. 2019. PMID: 31784108 Free PMC article.
Environmental arginine controls multinuclear giant cell metabolism and formation.
Brunner JS, Vulliard L, Hofmann M, Kieler M, Lercher A, Vogel A, Russier M, Brüggenthies JB, Kerndl M, Saferding V, Niederreiter B, Junza A, Frauenstein A, Scholtysek C, Mikami Y, Klavins K, Krönke G, Bergthaler A, O'Shea JJ, Weichhart T, Meissner F, Smolen JS, Cheng P, Yanes O, Menche J, Murray PJ, Sharif O, Blüml S, Schabbauer G. Brunner JS, et al. Nat Commun. 2020 Jan 22;11(1):431. doi: 10.1038/s41467-020-14285-1. Nat Commun. 2020. PMID: 31969567 Free PMC article.
microRNA-146a controls age-related bone loss.
Saferding V, Hofmann M, Brunner JS, Niederreiter B, Timmen M, Magilnick N, Hayer S, Heller G, Steiner G, Stange R, Boldin M, Schabbauer G, Weigl M, Hackl M, Grillari J, Smolen JS, Blüml S. Saferding V, et al. Among authors: brunner js. Aging Cell. 2020 Nov;19(11):e13244. doi: 10.1111/acel.13244. Epub 2020 Oct 21. Aging Cell. 2020. PMID: 33085187 Free PMC article.
The PI3K pathway preserves metabolic health through MARCO-dependent lipid uptake by adipose tissue macrophages.
Brunner JS, Vogel A, Lercher A, Caldera M, Korosec A, Pühringer M, Hofmann M, Hajto A, Kieler M, Garrido LQ, Kerndl M, Kuttke M, Mesteri I, Górna MW, Kulik M, Dominiak PM, Brandon AE, Estevez E, Egan CL, Gruber F, Schweiger M, Menche J, Bergthaler A, Weichhart T, Klavins K, Febbraio MA, Sharif O, Schabbauer G. Brunner JS, et al. Nat Metab. 2020 Dec;2(12):1427-1442. doi: 10.1038/s42255-020-00311-5. Epub 2020 Nov 16. Nat Metab. 2020. PMID: 33199895
38 results