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Chromothripsis drives the evolution of gene amplification in cancer.
Shoshani O, Brunner SF, Yaeger R, Ly P, Nechemia-Arbely Y, Kim DH, Fang R, Castillon GA, Yu M, Li JSZ, Sun Y, Ellisman MH, Ren B, Campbell PJ, Cleveland DW. Shoshani O, et al. Among authors: cleveland dw. Nature. 2021 Mar;591(7848):137-141. doi: 10.1038/s41586-020-03064-z. Epub 2020 Dec 23. Nature. 2021. PMID: 33361815 Free PMC article.
A two-step mechanism for epigenetic specification of centromere identity and function.
Fachinetti D, Folco HD, Nechemia-Arbely Y, Valente LP, Nguyen K, Wong AJ, Zhu Q, Holland AJ, Desai A, Jansen LE, Cleveland DW. Fachinetti D, et al. Among authors: cleveland dw. Nat Cell Biol. 2013 Sep;15(9):1056-66. doi: 10.1038/ncb2805. Epub 2013 Jul 21. Nat Cell Biol. 2013. PMID: 23873148 Free PMC article.
MYC Is a Major Determinant of Mitotic Cell Fate.
Topham C, Tighe A, Ly P, Bennett A, Sloss O, Nelson L, Ridgway RA, Huels D, Littler S, Schandl C, Sun Y, Bechi B, Procter DJ, Sansom OJ, Cleveland DW, Taylor SS. Topham C, et al. Among authors: cleveland dw. Cancer Cell. 2015 Jul 13;28(1):129-40. doi: 10.1016/j.ccell.2015.06.001. Cancer Cell. 2015. PMID: 26175417 Free PMC article.
Chronic centrosome amplification without tumorigenesis.
Vitre B, Holland AJ, Kulukian A, Shoshani O, Hirai M, Wang Y, Maldonado M, Cho T, Boubaker J, Swing DA, Tessarollo L, Evans SM, Fuchs E, Cleveland DW. Vitre B, et al. Among authors: cleveland dw. Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):E6321-30. doi: 10.1073/pnas.1519388112. Epub 2015 Nov 2. Proc Natl Acad Sci U S A. 2015. PMID: 26578792 Free PMC article.
Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS.
Sun S, Sun Y, Ling SC, Ferraiuolo L, McAlonis-Downes M, Zou Y, Drenner K, Wang Y, Ditsworth D, Tokunaga S, Kopelevich A, Kaspar BK, Lagier-Tourenne C, Cleveland DW. Sun S, et al. Among authors: cleveland dw. Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):E6993-7002. doi: 10.1073/pnas.1520639112. Epub 2015 Nov 30. Proc Natl Acad Sci U S A. 2015. PMID: 26621731 Free PMC article.
421 results