Yakubovich D - Search Results

1

A unique mechanism of inactivation gating of the Kv channel family member Kv7.1 and its modulation by PIP2 and calmodulin.

Lipinsky M, Tobelaim WS, Peretz A, Simhaev L, Yeheskel A, Yakubovich D, Lebel G, Paas Y, Hirsch JA, Attali B. Lipinsky M, et al. Among authors: yakubovich d. Sci Adv. 2020 Dec 18;6(51):eabd6922. doi: 10.1126/sciadv.abd6922. Print 2020 Dec. Sci Adv. 2020. PMID: 33355140 Free article.

2

External barium affects the gating of KCNQ1 potassium channels and produces a pore block via two discrete sites.

Gibor G, Yakubovich D, Peretz A, Attali B. Gibor G, et al. Among authors: yakubovich d. J Gen Physiol. 2004 Jul;124(1):83-102. doi: 10.1085/jgp.200409068. J Gen Physiol. 2004. PMID: 15226366 Free PMC article.

3

An inactivation gate in the selectivity filter of KCNQ1 potassium channels.

Gibor G, Yakubovich D, Rosenhouse-Dantsker A, Peretz A, Schottelndreier H, Seebohm G, Dascal N, Logothetis DE, Paas Y, Attali B. Gibor G, et al. Among authors: yakubovich d. Biophys J. 2007 Dec 15;93(12):4159-72. doi: 10.1529/biophysj.107.107987. Epub 2007 Aug 17. Biophys J. 2007. PMID: 17704175 Free PMC article.

4

Na+ promotes the dissociation between Galpha GDP and Gbeta gamma, activating G protein-gated K+ channels.

Rishal I, Keren-Raifman T, Yakubovich D, Ivanina T, Dessauer CW, Slepak VZ, Dascal N. Rishal I, et al. Among authors: yakubovich d. J Biol Chem. 2003 Feb 7;278(6):3840-5. doi: 10.1074/jbc.C200605200. Epub 2002 Dec 17. J Biol Chem. 2003. PMID: 12488455 Free article.

5

A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ.

Yakubovich D, Berlin S, Kahanovitch U, Rubinstein M, Farhy-Tselnicker I, Styr B, Keren-Raifman T, Dessauer CW, Dascal N. Yakubovich D, et al. PLoS Comput Biol. 2015 Nov 6;11(11):e1004598. doi: 10.1371/journal.pcbi.1004598. eCollection 2015 Nov. PLoS Comput Biol. 2015. PMID: 26544551 Free PMC article.

6

Andersen-Tawil Syndrome Is Associated With Impaired PIP₂ Regulation of the Potassium Channel Kir2.1.

Handklo-Jamal R, Meisel E, Yakubovich D, Vysochek L, Beinart R, Glikson M, McMullen JR, Dascal N, Nof E, Oz S. Handklo-Jamal R, et al. Among authors: yakubovich d. Front Pharmacol. 2020 May 15;11:672. doi: 10.3389/fphar.2020.00672. eCollection 2020. Front Pharmacol. 2020. PMID: 32499698 Free PMC article.

7

Convulsive seizures and some behavioral comorbidities are uncoupled in the Scn1a^A1783V Dravet syndrome mouse model.

Fadila S, Quinn S, Turchetti Maia A, Yakubovich D, Ovadia M, Anderson KL, Giladi M, Rubinstein M. Fadila S, et al. Among authors: yakubovich d. Epilepsia. 2020 Oct;61(10):2289-2300. doi: 10.1111/epi.16662. Epub 2020 Aug 31. Epilepsia. 2020. PMID: 32865826

8

Slow modal gating of single G protein-activated K+ channels expressed in Xenopus oocytes.

Yakubovich D, Pastushenko V, Bitler A, Dessauer CW, Dascal N. Yakubovich D, et al. J Physiol. 2000 May 1;524 Pt 3(Pt 3):737-55. doi: 10.1111/j.1469-7793.2000.00737.x. J Physiol. 2000. PMID: 10790155 Free PMC article.

9

Amplitude histogram-based method of analysis of patch clamp recordings that involve extreme changes in channel activity levels.

Yakubovich D, Rishal I, Dessauer CW, Dascal N. Yakubovich D, et al. J Mol Neurosci. 2009 Mar;37(3):201-11. doi: 10.1007/s12031-008-9117-z. Epub 2008 Jul 12. J Mol Neurosci. 2009. PMID: 18622586 Free PMC article.

10

In vivo, in vitro and in silico correlations of four de novo SCN1A missense mutations.

Nissenkorn A, Almog Y, Adler I, Safrin M, Brusel M, Marom M, Bercovich S, Yakubovich D, Tzadok M, Ben-Zeev B, Rubinstein M. Nissenkorn A, et al. Among authors: yakubovich d. PLoS One. 2019 Feb 8;14(2):e0211901. doi: 10.1371/journal.pone.0211901. eCollection 2019. PLoS One. 2019. PMID: 30735520 Free PMC article.

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