Chen J - Search Results

1

Targeting castration-resistant prostate cancer with a novel RORγ antagonist elaiophylin.

Zheng J, Wang J, Wang Q, Zou H, Wang H, Zhang Z, Chen J, Wang Q, Wang P, Zhao Y, Lu J, Zhang X, Xiang S, Wang H, Lei J, Chen HW, Liu P, Liu Y, Han F, Wang J. Zheng J, et al. Among authors: chen j, chen hw. Acta Pharm Sin B. 2020 Dec;10(12):2313-2322. doi: 10.1016/j.apsb.2020.07.001. Epub 2020 Jul 12. Acta Pharm Sin B. 2020. PMID: 33354503 Free PMC article.

2

The novel indomethacin derivative CZ-212-3 exerts antitumor effects on castration-resistant prostate cancer by degrading androgen receptor and its variants.

Wang H, Chang Z, Cai GD, Yang P, Chen JH, Yang SS, Guo YF, Wang MY, Zheng XH, Lei JP, Liu PQ, Zhao DP, Wang JJ. Wang H, et al. Acta Pharmacol Sin. 2022 Apr;43(4):1024-1032. doi: 10.1038/s41401-021-00738-w. Epub 2021 Jul 28. Acta Pharmacol Sin. 2022. PMID: 34321613 Free PMC article.

3

Exploring Marine-Derived Ascochlorins as Novel Human Dihydroorotate Dehydrogenase Inhibitors for Treatment of Triple-Negative Breast Cancer.

Luo X, Cai G, Guo Y, Gao C, Huang W, Zhang Z, Lu H, Liu K, Chen J, Xiong X, Lei J, Zhou X, Wang J, Liu Y. Luo X, et al. Among authors: chen j. J Med Chem. 2021 Sep 23;64(18):13918-13932. doi: 10.1021/acs.jmedchem.1c01402. Epub 2021 Sep 13. J Med Chem. 2021. PMID: 34516133

4

Therapeutic targeting RORγ with natural product N-hydroxyapiosporamide for small cell lung cancer by reprogramming neuroendocrine fate.

Chen J, Hu Y, Zhang J, Wang Q, Wu X, Huang W, Wang Q, Cai G, Wang H, Ou T, Feng W, Liu P, Liu Y, Wang J, Huang J, Wang J. Chen J, et al. Pharmacol Res. 2022 Apr;178:106160. doi: 10.1016/j.phrs.2022.106160. Epub 2022 Mar 6. Pharmacol Res. 2022. PMID: 35259480

5

Discovery of Highly Potent Daphnane Diterpenoids Uncovers Importin-β1 as a Druggable Vulnerability in Castration-Resistant Prostate Cancer.

Huang JL, Yan XL, Li W, Fan RZ, Li S, Chen J, Zhang Z, Sang J, Gan L, Tang GH, Chen H, Wang J, Yin S. Huang JL, et al. Among authors: chen j, chen h. J Am Chem Soc. 2022 Sep 28;144(38):17522-17532. doi: 10.1021/jacs.2c06449. Epub 2022 Sep 14. J Am Chem Soc. 2022. PMID: 36103720

6

Tumor mitochondrial oxidative phosphorylation stimulated by the nuclear receptor RORγ represents an effective therapeutic opportunity in osteosarcoma.

Zheng J, Wang Q, Chen J, Cai G, Zhang Z, Zou H, Zou JX, Liu Q, Ji S, Shao G, Li H, Li S, Chen HW, Lu L, Yuan Y, Liu P, Wang J. Zheng J, et al. Among authors: chen j, chen hw. Cell Rep Med. 2024 May 21;5(5):101519. doi: 10.1016/j.xcrm.2024.101519. Epub 2024 Apr 30. Cell Rep Med. 2024. PMID: 38692271

7

SOFA in sepsis: with or without GCS.

Wang L, Ma X, Zhou G, Gao S, Pan W, Chen J, Su L, He H, Long Y, Yin Z, Shu T, Zhou X; China National Critical Care Quality Control Centre Group (China-NCCQC). Wang L, et al. Among authors: chen j. Eur J Med Res. 2024 May 24;29(1):296. doi: 10.1186/s40001-024-01849-w. Eur J Med Res. 2024. PMID: 38790024

8

Incomplete tuberculosis reporting and registration to the surveillance system in southwestern China of Yunnan Province: an inventory survey.

Chen J, Qiu Y, Wu W, Pan Y, Yang R, Li L, Yang Y, Lu K, Xu L. Chen J, et al. BMC Public Health. 2024 May 25;24(1):1397. doi: 10.1186/s12889-024-18794-2. BMC Public Health. 2024. PMID: 38789991

9

MKI67 with arterial hypertension predict a poor survival for prostate cancer patients, a real-life investigation.

Zhou Y, Chen W, Jiang H, Zhang Y, Ma Z, Wang Z, Xu C, Jiang M, Chen J, Cao Z. Zhou Y, et al. Among authors: chen j. Clin Transl Oncol. 2024 May 24. doi: 10.1007/s12094-024-03505-5. Online ahead of print. Clin Transl Oncol. 2024. PMID: 38789889

10

Association of the retinol to all-trans retinoic acid pathway with autism spectrum disorder.

Feng YR, Zhang Q, Miao JK, Yang T, Chen J, Chen HY, Mou QH, Xiang XL, Long D, Wei QH, Wu Y, Li TY. Feng YR, et al. Among authors: chen j. World J Pediatr. 2024 May 24. doi: 10.1007/s12519-024-00815-0. Online ahead of print. World J Pediatr. 2024. PMID: 38789720

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